PDB entry 7ak3

View 7ak3 on RCSB PDB site
Description: CLK1 bound with CAF052
Class: transferase
Keywords: CLK1, Kinase, Inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2020-09-29, released 2020-11-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-11, with a file datestamp of 2020-11-06.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase CLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK1, CLK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49759 (2-End)
      • expression tag (1)
      • conflict (286)
    Domains in SCOPe 2.08: d7ak3a1, d7ak3a2
  • Heterogens: RH8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7ak3A (A:)
smhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaars
eiqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhi
rkmayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvd
fgsatyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdsk
ehlammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdv
eherlfdliqkmleydpakritlrealkhpffdllkksi

    Sequence, based on observed residues (ATOM records): (download) 
    >7ak3A (A:)
mhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarse
iqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhir
kmayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvdf
gsatyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdske
hlammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdve
herlfdliqkmleydpakritlrealkhpffdllkks