PDB entry 7aeh

View 7aeh on RCSB PDB site
Description: SARS-CoV-2 main protease in a covalent complex with a pyridine derivative of ABT-957, compound 1
Class: hydrolase
Keywords: covid-19, inhibitor, protease, HYDROLASE
Deposited on 2020-09-17, released 2021-07-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2'-O-methyltransferase
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: orf1ab
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7aeha_
  • Heterogens: R8H, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7aehA (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddvvycprhvictsedmlnpnyedllir
ksnhnflvqagnvqlrvighsmqncvlklkvdtanpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnftikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegn
fygpfvdrqtaqaagtdttitvnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaslkellqngmngrtilgsalledeftpfdvvrqc
sgvtf