PDB entry 7ado

View 7ado on RCSB PDB site
Description: cryo-em structure of human er membrane protein complex in lipid nanodiscs
Deposited on 2020-09-15, released 2020-12-02
The last revision was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: EM
Resolution: 3.39 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ER membrane protein complex subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC1, KIAA0090, PSEC0263
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ER membrane protein complex subunit 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC2, KIAA0103, TTC35
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ER membrane protein complex subunit 3
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC3, TMEM111
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ER Membrane Protein Complex Subunit 4
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC4, TMEM85, HSPC184, PIG17
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Membrane magnesium transporter 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MMGT1, EMC5, TMEM32
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ER membrane protein complex subunit 6
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC6, TMEM93
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: ER membrane protein complex subunit 7
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC7, C11orf3, C15orf24, HT022, UNQ905/PRO1926
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: ER membrane protein complex subunit 8
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC8, C16orf2, C16orf4, COX4AL, COX4NB, FAM158B, NOC4
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: ER membrane protein complex subunit 10
    Species: Homo sapiens [TaxId:9606]
    Gene: EMC10, C19orf63, HSM1, INM02, UNQ764/PRO1556
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Unassigned helix
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7ADO (0-15)
  • Heterogens: NAG, PCW

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7adoA (A:)
maaewasrfwlwatllipaaavyedqvgkfdwrqqyvgkvkfaslefspgskklvvatek
nviaalnsrtgeilwrhvdkgtaegavdamllhgqdvitvsnggrimrswetnigglnwe
itldsgsfqalglvglqesvryiavlkkttlalhhlssghlkwvehlpesdsihyqmvys
ygsgvvwalgvvpfshvnivkfnvedgeivqqvrvstpwlqhlsgacgvvdeavlvcpdp
ssrslqtlaletewelrqiplqsldlefgsgfqprvlptqpnpvdasraqfflhlspshy
allqyhygtlsllknfpqtalvsfattgektvaavmacrnevqkssssedgsmgsfseks
sskdslacfnqtytinlylvetgrrlldttitfsleqsgtrperlyiqvflkkddsvgyr
alvqtedhlllflqqlagkvvlwsreeslaevvclemvdlpltgaqaelegefgkkadgl
lgmflkrlssqlillqawtshlwkmfydarkprsqikneinidtlardefnlqkmmvmvt
asgklfgiesssgtilwkqylpnvkpdssfklmvqrttahfphppqctllvkdkesgmss
lyvfnpifgkwsqvappvlkrpilqslllpvmdqdyakvllliddeykvtafpatrnvlr
qlhelapsiffylvdaeqgrlcgyrlrkdlttelsweltippevqrivkvkgkrssehvh
sqgrvmgdrsvlykslnpnllavvtestdahhertfigiflidgvtgriihssvqkkakg
pvhivhsenwvvyqywntkarrneftvlelyegteqynatafssldrpqlpqvlqqsyif
pssisameatitergitsrhlliglpsgailslpkalldprrpeipteqsreenlipysp
dvqihaerfinynqtvsrmrgiytapsglestclvvaygldiyqtrvypskqfdvlkddy
dyvlissvlfglvfatmitkrlaqvkllnrawr

    Sequence, based on observed residues (ATOM records):
    >7adoA (A:)
yedqvgkfdwrqqyvgkvkfaslefspgskklvvateknviaalnsrtgeilwrhvdkgt
aegavdamllhgqdvitvsnggrimrswetnigglnweitldsgsfqalglvglqesvry
iavlkkttlalhhlssghlkwvehlpesdsihyqmvysygsgvvwalgvvpfshvnivkf
nvedgeivqqvrvstpwlqhlsgacgvvdeavlvcpdpssrslqtlaletewelrqiplq
sldlefgsgfqprvlptqpnpvdasraqfflhlspshyallqyhygtlsllknfpqtalv
sfattgektvaavmacrnfnqtytinlylvetgrrlldttitfsleqsgtrperlyiqvf
lkvgyralvqtedhlllflqqlagkvvlwsreeslaevvclemvdlpltgaqaelegefl
lgmflkrlssqlillqawtshlnidtlardefnlqkmmvmvtasgklfgiesssgtilwk
qylpnvkpdssfklmvqrttahfphppqctllvkdkesgmsslyvfnpifgkwsqvappv
lkrpilqslllpvmdqdyakvllliddeykvtafpatrnvlrqlhelapsiffylvdaeq
grlcgyrlrkdlttelsweltippevqrivkvkgkrssehvhsqgrvmgdrsvlykslnp
nllavvtestdahhertfigiflidgvtgriihssvqkkakgpvhivhsenwvvyqywnt
karrneftvlelyegteqynatafssldrpqlpqvlqqsyifpssisameatitergits
rhlliglpsgailslpkalldprrpeipteqsreenlipyspdvqihaerfinynqtvsr
mrgiytapsglestclvvaygldiyqtrvypskqfdvlkddydyvlissvlfglvfatmi
tkrlaqvkllnrawr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7adoB (B:)
makvselydvtweemrdkmrkwreensrnseqivevgeelineyasklgddiwiiyeqvm
iaaldygrddlalfclqelrrqfpgshrvkrltgmrfeameryddaiqlydrilqedptn
taarkrkiairkaqgknveairelneyleqfvgdqeawhelaelyinehdyakaafclee
lmmtnphnhlycqqyaevkytqgglenlelsrkyfaqalklnnrnmralfglymsashia
snpkasaktkkdnmkyaswaasqinrayqfagrskketkyslkavedmletlqitqs

    Sequence, based on observed residues (ATOM records):
    >7adoB (B:)
weemrdkmrkwreensrnseqivevgeelineyasklgddiwiiyeqvmiaaldygrddl
alfclqelrrqfpgshrvkrltgmrfeameryddaiqlydrilqedptntaarkrkiair
kaqgknveairelneyleqfvgdqeawhelaelyinehdyakaafcleelmmtnphnhly
cqqyaevkytqgglenlelsrkyfaqalklnnrnmralfglymsashiasnpkasaktkk
dnmkyaswaasqinrayqfagryslkavedmletl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7adoC (C:)
magpellldsnirlwvvlpiviitffvgmirhyvsillqsdkkltqeqvsdsqvlirsrv
lrengkyipkqsfltrkyyfnnpedgffkktkrkvvppspmtdptmltdmmkgnvtnvlp
miliggwinmtfsgfvttkvpfpltlrfkpmlqqgielltldaswvssaswyflnvfglr
siyslilgqdnaadqsrmmqeqmtgaamampadtnkafktewealeltdhqwalddveee
lmakdlhfegmfkkelqtsif

    Sequence, based on observed residues (ATOM records):
    >7adoC (C:)
pellldsnirlwvvlpiviitffvgmirhyvsillqsdkkltqeqvsdsqvlirsrvlre
ngkyipkqsfltrkyyfnnpedgffkktkrnvtnvlpmiliggwinmtfsgfvttkvpfp
ltlrfkpmlqqgielltldaswvssaswyflnvfglrsiyslildtnkafktewealelt
dhqwalddveeelmakdlhfegm

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7adoD (D:)
mtaqgglvanrgrrfkwaielsgpgggsrgrsdrgsgqgdslypvgyldkqvpdtsvqet
drilvekrcwdialgplkqipmnlfimymagntisifptmmvcmmawrpiqalmaisatf
kmlesssqkflqglvylignlmglalavykcqsmgllpthasdwlafieppermefsggg
lll

    Sequence, based on observed residues (ATOM records):
    >7adoD (D:)
rfkwaielsypvgyldkqvpnlmglalavykcqsmgllpthasdwlafieppermefsgg
glll

  • Chain 'E':
    Sequence, based on SEQRES records:
    >7adoE (E:)
mapslwkglvgiglfalahaafsaaqhrsymrltekedeslpidivlqtllafavtcygi
vhiagefkdmdatselknktfdtlrnhpsfyvfnhrgrvlfrpsdtanssnqdalssnts
lklrkleslrrdykddddk

    Sequence, based on observed residues (ATOM records):
    >7adoE (E:)
slwkglvgiglfalahaafsaaqhrsymrltekedeslpidivlqtllafavtcygivhi
agefkdmdatselknktfdtlrnhpsfyvfnhrgrvl

  • Chain 'F':
    Sequence, based on SEQRES records:
    >7adoF (F:)
maavvakregppfiseaavrgnaavldycrtsvsalsgatagilgltglygfifyllasv
llslllilkagrrwnkyfksrrplftggligglftyvlfwtflygmvhvy

    Sequence, based on observed residues (ATOM records):
    >7adoF (F:)
ppfiseaavrgnaavldycrtsvsalsgatagilgltglygfifyllasvllslllilka
grrwnkyfksrrplftggligglftyvlfwtflygmvhvy

  • Chain 'G':
    Sequence, based on SEQRES records:
    >7adoG (G:)
maaalwgffpvllllllsgdvqssevpgaaaegsggsgvgigdrfkiegravvpgvkpqd
wisaarvlvdgeehvgflktdgsfvvhdipsgsyvvevvspayrfdpvrvditskgkmra
ryvnyiktsevvrlpyplqmkssgppsyfikreswgwtdflmnpmvmmmvlpllifvllp
kvvntsdpdmrremeqsmnmlnsnhelpdvsefmtrlfsskssgksssgssktgksgagk
rr

    Sequence, based on observed residues (ATOM records):
    >7adoG (G:)
fkiegravvpgvkpqdwisaarvlvhvgflksfvvhdipsgsyvvevvspayrfdpvrvd
ikmraryvnyiktsevvrlpyplqmkssgppsyfikr

  • Chain 'H':
    Sequence, based on SEQRES records:
    >7adoH (H:)
mpgvklttqayckmvlhgakyphcavngllvaekqkprkehlplggpgahhtlfvdcipl
fhgtlalapmlevaltlidswckdhsyviagyyqanervkdaspnqvaekvasriaegfs
dtalimvdntkftmdcvaptihvyehhenrwrcrdphhdycedwpeaqrisaslldsrsy
etlvdfdnhlddirndwtnpeinkavlhlc

    Sequence, based on observed residues (ATOM records):
    >7adoH (H:)
vklttqayckmvlhgakyphcavngllvaetlfvdciplfhgtlalapmlevaltlidsw
ckdhsyviagyyqanervkdaspnqvaekvasriaegfsdtalimvdntkftmtihvyeh
henrwrcrdphpeaqrisaslldsrsyetlvdfdnhlddirndwtnpeinkavlhl

  • Chain 'I':
    Sequence, based on SEQRES records:
    >7adoI (I:)
maaaasagatrllllllmavaapsrargsgcragtgargagaegregeacgtvglllehs
feiddsanfrkrgsllwnqqdgtlslsqrqlseeergrlrdvaalnglyrvriprrpgal
dgleaggyvssfvpacslveshlsdqltlhvdvagnvvgvsvvthpggcrghevedvdle
lfntsvqlqppttapgpetaafierlemeqaqkaknpqeqksffakywmyiipvvlflmm
sgapdtggqgggggggggggsgr

    Sequence, based on observed residues (ATOM records):
    >7adoI (I:)
tvglllehsfeiddsanfrkrgsllwnqqdgtlslsqrqlseeergrlrdvaalnglyrv
riprryvssfvpacslveshlsdqltlhvdvagnvvgvsvvthpggcrghevedvdlelf
ntsvqlqppttapgpetaafie

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >7adoK (K:)
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