PDB entry 7acc

View 7acc on RCSB PDB site
Description: human GTP cyclohydrolase I feedback regulatory protein (GFRP)
Class: protein binding
Keywords: GTP cyclohydrolase 1 feedback regulatory protein, regulatory protein, L-phenylalanine binding (Phe) synthesis allosteric regulation, PROTEIN BINDING
Deposited on 2020-09-10, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-23, with a file datestamp of 2020-12-18.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7acca_
  • Chain 'B':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7accb_
  • Chain 'C':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30047 (2-85)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7accc1, d7accc2
  • Chain 'D':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7accd_
  • Chain 'E':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30047 (2-85)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7acce1, d7acce2
  • Chain 'F':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7accf_
  • Chain 'G':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30047 (2-85)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7accg1, d7accg2
  • Chain 'H':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30047 (2-85)
      • expression tag (1)
    Domains in SCOPe 2.08: d7acch1, d7acch2
  • Chain 'I':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7acci_
  • Chain 'J':
    Compound: GTP cyclohydrolase 1 feedback regulatory protein
    Species: Homo sapiens [TaxId:9606]
    Gene: GCHFR, GFRP
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7accj_
  • Heterogens: K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7accA (A:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accA (A:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7accB (B:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accB (B:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7accC (C:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >7accD (D:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accD (D:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7accE (E:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >7accF (F:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accF (F:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7accG (G:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >7accH (H:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accH (H:)
hmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldk
lerrgfrvlsmtgvgqtlvwclhke

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >7accI (I:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accI (I:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >7accJ (J:)
shmpyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivld
klerrgfrvlsmtgvgqtlvwclhke

    Sequence, based on observed residues (ATOM records): (download) 
    >7accJ (J:)
pyllistqirmevgptmvgdeqsdpelmqhlgaskrralgnnfyeyyvddpprivldkle
rrgfrvlsmtgvgqtlvwclhke