PDB entry 7ab2

View 7ab2 on RCSB PDB site
Description: crystal structure of mertk kinase domain in complex with unc2025
Deposited on 2020-09-05, released 2020-10-28
The last revision was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase Mer
    Species: Homo sapiens [TaxId:9606]
    Gene: MERTK, MER
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12866 (4-End)
      • expression tag (1-3)
      • engineered mutation (24)
      • engineered mutation (126)
      • engineered mutation (135)
      • engineered mutation (289)
  • Heterogens: R6N, CL, DMS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7ab2A (A:)
gshmeelqnkledvvidrnllilgrilgegefgsvmegnlkqedgtslkvavktmkldns
sqreieeflseaacmkdfshpnvirllgvciemssqgipkpmvilpfmkygdlhtyllys
rletgprhiplqtllrfmvdialgmeylsnrnflhrdlaarncmlrddmtvcvadfglsk
kiysgdyyrqgriakmpvkwiaiesladrvytsksdvwafgvtmweiatrgmtpypgvqn
hemydyllhghrlkqpedcldelyeimyscwrtdpldrptfsvlrlqlerlleslpdv

    Sequence, based on observed residues (ATOM records):
    >7ab2A (A:)
shmeelqnkledvvidrnllilgrilgegefgsvmegnlkqedgtslkvavktmsqreie
eflseaacmkdfshpnvirllgvciemssqgipkpmvilpfmkygdlhtyllysrletgp
rhiplqtllrfmvdialgmeylsnrnflhrdlaarncmlrddmtvcvadfpvkwiaiesl
adrvytsksdvwafgvtmweiatrgmtpypgvqnhemydyllhghrlkqpedcldelyei
myscwrtdpldrptfsvlrlqlerlleslp