PDB entry 7a96

View 7a96 on RCSB PDB site
Description: sars-cov-2 spike glycoprotein with 1 ace2 bound and 1 rbd erect in anticlockwise direction
Deposited on 2020-09-01, released 2020-09-16
The last revision was dated 2020-12-16, with a file datestamp of 2020-12-11.
Experiment type: EM
Resolution: 4.8 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (1016-1017)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (1016-1017)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2
      • engineered mutation (1016-1017)
  • Chain 'D':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7a96A (A:)
mgilpspgmpallslvsllsvllmgcvaetgmfvflvllplvssqcvnlttrtqlppayt
nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndg
vyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknn
kswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtp
inlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgy
lqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrf
pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
adttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadql
tptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnsprrarsvas
qsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstec
snlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdp
skpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdem
iaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfns
aigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppea
evqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhl
msfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnf
yepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdi
sginasvvniqkeidrlnevaknlneslidlqelgkyeqsgrenlyfqggggsgyipeap
rdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7a96A (A:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvtkr
fdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcnd
pflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknid
gyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgw
tagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvncn
vfqtragcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsia
iptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiave
qdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvaqkfngl
tvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlye
nqklianqfnsaigkiqdslssalgklqdvvnqnaqalntlvkqlssnfgaissvlndil
srldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvd
fcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngth
wfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7a96B (B:)
mgilpspgmpallslvsllsvllmgcvaetgmfvflvllplvssqcvnlttrtqlppayt
nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndg
vyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknn
kswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtp
inlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgy
lqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrf
pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
adttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadql
tptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnsprrarsvas
qsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstec
snlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdp
skpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdem
iaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfns
aigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppea
evqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhl
msfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnf
yepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdi
sginasvvniqkeidrlnevaknlneslidlqelgkyeqsgrenlyfqggggsgyipeap
rdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7a96B (B:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvtkr
fdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcnd
pflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknid
gyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgw
tagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvncn
vfqtragcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsia
iptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiave
qdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvaqkfngl
tvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlye
nqklianqfnsaigkiqdslssalgklqdvvnqnaqalntlvkqlssnfgaissvlndil
srldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvd
fcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngth
wfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'C':
    Sequence, based on SEQRES records:
    >7a96C (C:)
mgilpspgmpallslvsllsvllmgcvaetgmfvflvllplvssqcvnlttrtqlppayt
nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndg
vyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknn
kswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtp
inlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgy
lqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrf
pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklnd
lcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggny
nylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyr
vvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdi
adttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadql
tptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtnsprrarsvas
qsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstec
snlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdp
skpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdem
iaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfns
aigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldppea
evqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhl
msfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnf
yepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdi
sginasvvniqkeidrlnevaknlneslidlqelgkyeqsgrenlyfqggggsgyipeap
rdgqayvrkdgewvllstflghhhhhh

    Sequence, based on observed residues (ATOM records):
    >7a96C (C:)
qcvnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvtkr
fdnpvlpfndgvyfasteksniirgwifgttldsktqsllivnnatnvvikvcefqfcnd
pflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknid
gyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgw
tagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnf
rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfk
cygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawns
nnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfq
ptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkk
flpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvncs
nvfqtragcligaehvnnsyecdipigagicasyqtsqsiiaytmslgaensvaysnnsi
aiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiav
eqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkaqkfngl
tvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlye
nqklianqfnsaigkiqdslssalgklqdvvnqnaqalntlvkqlssnfgaissvlndil
srldppeaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvd
fcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngth
wfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeld

  • Chain 'D':
    Sequence, based on SEQRES records:
    >7a96D (D:)
metdtlllwvlllwvpgstgstieeqaktfldkfnheaedlfyqsslaswnyntniteen
vqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlnt
ilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrp
lyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplye
hlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamv
dqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfri
lmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhl
ksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkww
emkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegp
lhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdq
nknsfvgwstdwspyaddykddddkwshpqfekgggsgggsggssawshpqfek

    Sequence, based on observed residues (ATOM records):
    >7a96D (D:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvccllle
pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrg
dyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispigclpah
llgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtq
gfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmay
aaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqalt
ivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdpaslfh
vsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksep
wtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspy