PDB entry 7a7h

View 7a7h on RCSB PDB site
Description: Crystal structure of PPARgamma in complex with compound TK90
Class: DNA binding protein
Keywords: complex, Structural Genomics, Structural Genomics Consortium, SGC, DNA BINDING PROTEIN
Deposited on 2020-08-28, released 2021-08-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-08-04, with a file datestamp of 2021-07-30.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (2-276)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d7a7ha1, d7a7ha2
  • Heterogens: TK9, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >7a7hA (A:)
    smqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmged
    kikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllky
    gvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleld
    dsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmt
    dlrqivtehvqllqvikktetdmslhpllqeiykdly
    

    Sequence, based on observed residues (ATOM records): (download)
    >7a7hA (A:)
    smqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgsk
    evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
    kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
    drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
    ikkteslhpllqeiykd