PDB entry 7a5x

View 7a5x on RCSB PDB site
Description: two copies of the catalytic domain of nana sialidase from streptococcus pneumoniae juxtaposed in the p212121 space group, in complex with dana derivatized with a peg linker on the glycerol group.
Deposited on 2020-08-24, released 2020-11-18
The last revision was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: sialidase a
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: nanA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: sialidase a
    Species: Streptococcus pneumoniae [TaxId:1313]
    Gene: nanA
    Database cross-references and differences (RAF-indexed):
  • Heterogens: R7H, SO4, CL, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >7a5xA (A:)
mghhhhhhhhhhssghiddddkhmpegaaltektdifesgrngkpnkdgiksyripallk
tdkgtliagaderrlhssdwgdigmvirrsedngktwgdrvtitnlrdnpkasdpsigsp
vnidmvlvqdpetkrifsiydmfpegkgifgmssqkeeaykkidgktyqilyregekgay
tirengtvytpdgkatdyrvvvdpvkpaysdkgdlykgnqllgniyfttnktspfriakd
sylwmsysdddgktwsapqditpmvkadwmkflgvgpgtgivlrngphkgrilipvyttn
nvshlngsqssriiysddhgktwhageavndnrqvdgqkihsstmnnrraqntestvvql
nngdvklfmrgltgdlqvatskdggvtwekdikrypqvkdvyvqmsaihtmhegkeyiil
snaggpkrengmvhlarveengeltwlkhnpiqkgefaynslqelgngeygilyehtekg
qnaytlsfrkfnwdflsk

    Sequence, based on observed residues (ATOM records):
    >7a5xA (A:)
gaaltektdifesgrngkpnkdgiksyripallktdkgtliagaderrlhssdwgdigmv
irrsedngktwgdrvtitnlrdnpkasdpsigspvnidmvlvqdpetkrifsiydmfpeg
kgifgmssqkeeaykkidgktyqilyregekgaytirengtvytpdgkatdyrvvvdpvk
paysdkgdlykgnqllgniyfttnktspfriakdsylwmsysdddgktwsapqditpmvk
adwmkflgvgpgtgivlrngphkgrilipvyttnnvshlngsqssriiysddhgktwhag
eavndnrqvdgqkihsstmnnrraqntestvvqlnngdvklfmrgltgdlqvatskdggv
twekdikrypqvkdvyvqmsaihtmhegkeyiilsnaggpkrengmvhlarveengeltw
lkhnpiqkgefaynslqelgngeygilyehtekgqnaytlsfrkfnwdflsk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >7a5xB (B:)
mghhhhhhhhhhssghiddddkhmpegaaltektdifesgrngkpnkdgiksyripallk
tdkgtliagaderrlhssdwgdigmvirrsedngktwgdrvtitnlrdnpkasdpsigsp
vnidmvlvqdpetkrifsiydmfpegkgifgmssqkeeaykkidgktyqilyregekgay
tirengtvytpdgkatdyrvvvdpvkpaysdkgdlykgnqllgniyfttnktspfriakd
sylwmsysdddgktwsapqditpmvkadwmkflgvgpgtgivlrngphkgrilipvyttn
nvshlngsqssriiysddhgktwhageavndnrqvdgqkihsstmnnrraqntestvvql
nngdvklfmrgltgdlqvatskdggvtwekdikrypqvkdvyvqmsaihtmhegkeyiil
snaggpkrengmvhlarveengeltwlkhnpiqkgefaynslqelgngeygilyehtekg
qnaytlsfrkfnwdflsk

    Sequence, based on observed residues (ATOM records):
    >7a5xB (B:)
gaaltektdifesgrngkpnkdgiksyripallktdkgtliagaderrlhssdwgdigmv
irrsedngktwgdrvtitnlrdnpkasdpsigspvnidmvlvqdpetkrifsiydmfpeg
kgifgmssqkeeaykkidgktyqilyregekgaytirengtvytpdgkatdyrvvvdpvk
paysdkgdlykgnqllgniyfttnktspfriakdsylwmsysdddgktwsapqditpmvk
adwmkflgvgpgtgivlrngphkgrilipvyttnnvshlngsqssriiysddhgktwhag
eavndnrqvdgqkihsstmnnrraqntestvvqlnngdvklfmrgltgdlqvatskdggv
twekdikrypqvkdvyvqmsaihtmhegkeyiilsnaggpkrengmvhlarveengeltw
lkhnpiqkgefaynslqelgngeygilyehtekgqnaytlsfrkfnwdflsk