PDB entry 7a3q

View 7a3q on RCSB PDB site
Description: Crystal structure of dengue 4 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10
Class: viral protein
Keywords: VIRAL PROTEIN, FLAVIVIRUS, CLASS 2 FUSION PROTEIN, DENGUE, Antibody
Deposited on 2020-08-18, released 2021-12-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-12-22, with a file datestamp of 2021-12-17.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Envelope protein E
    Species: DENGUE VIRUS 4 [TaxId:11070]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7a3qa1, d7a3qa2
  • Chain 'B':
    Compound: Envelope protein E
    Species: DENGUE VIRUS 4 [TaxId:11070]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7a3qb1, d7a3qb2
  • Chain 'H':
    Compound: single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7A3Q (0-143)
  • Chain 'I':
    Compound: single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7A3Q (0-143)
  • Chain 'L':
    Compound: single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7A3Q (0-153)
  • Chain 'M':
    Compound: single chain variable fragment
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 7A3Q (0-153)
  • Heterogens: NAG, 3CX, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7a3qA (A:)
mrcvgvgnrdfvegvsggawvdlvlehggcvttmaqgkptldfeltkttakevallrtyc
ieasisnittatrcptqgepylkeeqdqqyicrrdvvdrgwgngcglfgkggvvtcakfs
csgkitgnlvqienleytvvvtvhngdthavgndtsnhgvtamitprspsvevklpdyge
ltldceprsgidfnemilmkmkkktwlvhkqwfldlplpwtagadtsevhwnykermvtf
kvphakrqdvtvlgsqegamhsalagatevdsgdgnhmfaghlkckvrmeklrikgmsyt
mcsgkfsidkemaetqhgttvvkvkyegagapckvpieirdvnkekvvgriisstplaen
tnsvtnieleppfgdsyivigvgnsaltlhwfrkg

    Sequence, based on observed residues (ATOM records): (download) 
    >7a3qA (A:)
mrcvgvgnrdfvegvwvdlvlehggcvttmaqgkptldfeltkttakevallrtycieas
isnittatrcptqgepylkeeqdqqyicrrdvvdrgwgngcglfgkggvvtcakfscsgk
itgnlvqienleytvvvtvhngvtamitprspsvevklpdygeltldceprsgidfnemi
lmkmkkktwlvhkqwfldlplpwtagvhwnykermvtfkvphakrqdvtvlgsqegamhs
alagatevdsgdgnhmfaghlkckvrmeklrikgmsytmcsgkfsidkemaetqhgttvv
kvkyegagapckvpieirdvnkekvvgriisstplaentnsvtnieleppfgdsyivigv
gnsaltlhwfrk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7a3qB (B:)
mrcvgvgnrdfvegvsggawvdlvlehggcvttmaqgkptldfeltkttakevallrtyc
ieasisnittatrcptqgepylkeeqdqqyicrrdvvdrgwgngcglfgkggvvtcakfs
csgkitgnlvqienleytvvvtvhngdthavgndtsnhgvtamitprspsvevklpdyge
ltldceprsgidfnemilmkmkkktwlvhkqwfldlplpwtagadtsevhwnykermvtf
kvphakrqdvtvlgsqegamhsalagatevdsgdgnhmfaghlkckvrmeklrikgmsyt
mcsgkfsidkemaetqhgttvvkvkyegagapckvpieirdvnkekvvgriisstplaen
tnsvtnieleppfgdsyivigvgnsaltlhwfrkg

    Sequence, based on observed residues (ATOM records): (download) 
    >7a3qB (B:)
mrcvgvgnrdfvegvsvdlvlehggcvttmaqgkptldfeltkttakevallrtycieas
isnittatrcptqgepylkeeqdqqyicrrdvvdrgwgngcglfgkggvvtcakfscsgk
itgnlvqienleytvvvtvhnhgvtamitprspsvevklpdygeltldceprsgidfnem
ilmkmkkktwlvhkqwfldlplpwtagevhwnykermvtfkvpqdvtvlgsqegamhsal
agatevdhmfaghlkckvrmeklrikgmsytmcsgkfsidkemaetqhgttvvkvkyega
gapckvpieirdvnkekvvgriisstplaentnsvtnieleppfgdsyivigvgnsaltl
hwfrkg

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.