PDB entry 7a2o

View 7a2o on RCSB PDB site
Description: Crystal structure of the Fyn SH3 domain L112V-S114N-S115T-E121L-R123H mutant at pH 4.5
Class: protein binding
Keywords: beta barrel, SH3 domain, PROTEIN BINDING
Deposited on 2020-08-18, released 2021-08-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-08-25, with a file datestamp of 2021-08-20.
Experiment type: XRAY
Resolution: 0.94 Å
R-factor: N/A
AEROSPACI score: 0.97 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase Fyn
    Species: Homo sapiens [TaxId:9606]
    Gene: FYN
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06241 (0-59)
      • engineered mutation (29)
      • engineered mutation (31-32)
      • engineered mutation (38)
      • engineered mutation (40)
    Domains in SCOPe 2.08: d7a2oa_
  • Heterogens: PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >7a2oA (A:)
gvtlfvalydyearteddlsfhkgekfqivnntegdwwlahslttgetgyipsnyvapvd