PDB entry 7a22

View 7a22 on RCSB PDB site
Description: Crystal structure of human protein kinase CK2alpha' (CSNK2A2 gene product) in complex with the ATP-competitive inhibitor 5,6,7-tribromo-1H-triazolo[4,5-b]pyridine
Class: transferase
Keywords: protein kinase CK2, casein kinase 2, ATP-competitive inhibitor, TRANSFERASE
Deposited on 2020-08-15, released 2020-12-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-13, with a file datestamp of 2021-01-08.
Experiment type: XRAY
Resolution: 1.01 Å
R-factor: N/A
AEROSPACI score: 0.89 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Casein kinase II subunit alpha'
    Species: Homo sapiens [TaxId:9606]
    Gene: CSNK2A2, CK2A2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7a22a_
  • Heterogens: QWW, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7a22A (A:)
mgsshhhhhhsqdpmpgpaagsrarvyaevnslrsreywdyeahvpswgnqddyqlvrkl
grgkysevfeainitnnervvvkilkpvkkkkikrevkilenlrggtniiklidtvkdpv
sktpalvfeyinntdfkqlyqiltdfdirfymyellkaldychskgimhrdvkphnvmid
hqqkklrlidwglaefyhpaqeynvrvasryfkgpellvdyqmydysldmwslgcmlasm
ifrrepffhgqdnydqlvriakvlgteelygylkkyhidldphfndilgqhsrkrwenfi
hsenrhlvspealdlldkllrydhqqrltakeamehpyfypvvkeqsqpsadnavlssgl
taar

    Sequence, based on observed residues (ATOM records): (download) 
    >7a22A (A:)
agsrarvyaevnslrsreywdyeahvpswgnqddyqlvrklgrgkysevfeainitnner
vvvkilkpvkkkkikrevkilenlrggtniiklidtvkdpvsktpalvfeyinntdfkql
yqiltdfdirfymyellkaldychskgimhrdvkphnvmidhqqkklrlidwglaefyhp
aqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrrepffhgqdnydqlvr
iakvlgteelygylkkyhidldphfndilgqhsrkrwenfihsenrhlvspealdlldkl
lrydhqqrltakeamehpyfypvvkeqs