SCOPe 2.08: Structural Classification of Proteins

PDB entry 7a1d

View 7a1d on RCSB PDB site
Description: cryo-em map of the large glutamate dehydrogenase composed of 180 kda subunits from mycobacterium smegmatis (open conformation)
Deposited on 2020-08-12, released 2021-06-09
The last revision was dated 2021-10-06, with a file datestamp of 2021-10-01.
Experiment type: EM
Resolution: 4.19 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: nad-specific glutamate dehydrogenase
Species: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
Gene: gdh, MSMEG_4699, MSMEI_4582
Database cross-references and differences (RAF-indexed):
- Uniprot A0R1C2 (17-1610)
  - initiating methionine (0)
  - expression tag (1-16)
Chain 'B':
Compound: nad-specific glutamate dehydrogenase
Species: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
Gene: gdh, MSMEG_4699, MSMEI_4582
Database cross-references and differences (RAF-indexed):
- Uniprot A0R1C2 (17-1610)
  - initiating methionine (0)
  - expression tag (1-16)
Chain 'C':
Compound: nad-specific glutamate dehydrogenase
Species: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
Gene: gdh, MSMEG_4699, MSMEI_4582
Database cross-references and differences (RAF-indexed):
- Uniprot A0R1C2 (17-1610)
  - initiating methionine (0)
  - expression tag (1-16)
Chain 'D':
Compound: nad-specific glutamate dehydrogenase
Species: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) [TaxId:246196]
Gene: gdh, MSMEG_4699, MSMEI_4582
Database cross-references and differences (RAF-indexed):
- Uniprot A0R1C2 (17-1610)
  - initiating methionine (0)
  - expression tag (1-16)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>7a1dA (A:)
mhhhhhhenlyfqgaasmirrlsvaflstyrgpqadapgvtstgplavaahddlvsddlv
aahyrlasmrapgetkaavypgdagsgaalqivtdqapmlvdsvtvllhrhgiaytaimn
pvfrvrrgldgelldvrpaaeaapgdgadecwilvpitaaadgealteatrlvpgilaea
rqigldsgamiaalhglandlatdleghfpnaerkevaallrwladghfvllgyqqcvvg
dgnaevdpasrlgvlrlrndvlppltdsddllvlaqatmpsylrygaypyivvvrespga
srviehrfvglftvaamnanaleiplisrrveealamahrdpshpgqllrdiiqtiprpe
lfalsskqllemalavvdlgsrrrtllflradhlahfvsclvylprdryttavrlemqdi
lvrelggagidysarvsespwavvhftvrlpegtaadsvdtslenesriqdllteatrnw
gdrmisaaaaasispaalehyahafpedykqafapqdaiadisliealqddsvklvladt
aedrvwkltwylgghsaslsellpmlqsmgvvvleerpftlrrtdglpvwiyqfkisphp
siphapdaeaqrdtaqrfadavtaiwhgrveidrfnelvmragltwqqvvvlrayakylr
qagfpysqshiesvlnenphttrslidlfealfdpsqetdgrrdaqgaaaavaadidalv
sldtdrvlrafanlieatlrtnyfvarpdsararnvlafklnplvikelplprpkfeifv
ysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavknavivpvgakggfvvkr
pptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavvtppevvrrdgedayl
vvaadkgtatfsdianevaksygfwlgdafasggsigydhkamgitakgawesvkrhfre
mgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswderk
rlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppalikai
lkapvdllwnggigtyikaeteadadvgdrandqirvcgnqvrakvigeggnlgvtalgr
iefdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevg
elvladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrrada
gigltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshql
rreiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraag
dagvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlr
gddkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfal
mdhlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekia
ewettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrtsgtgttg

Sequence, based on observed residues (ATOM records):

>7a1dA (A:)
daiadisliealqddsvklvladtaedrvwkltwylgghsaslsellpmlqsmgvvvlee
rpftlrrtdglpvwiyqfkisphpsiphapdaeaqrdtaqrfadavtaiwhgrveidrfn
elvmragltwqqvvvlrayakylrqagfpysqshiesvlnenphttrslidlfealfdps
qetdgrrdaqgaaaavaadidalvsldtdrvlrafanlieatlrtnyfvnvlafklnplv
ikelplprpkfeifvysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavkna
vivpvgakggfvvkrpptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavv
tppevvrrdgedaylvvaadkgtatfsdianevaksygfwlgdafagitakgawesvkrh
fremgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswd
erkrlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppali
kailkapvdllwnggigtyikaeteadadndqirvcgnqvrakvigeggnlgvtalgrie
fdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevgel
vladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrradagi
gltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshqlrr
eiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraagda
gvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlrgd
dkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfalmd
hlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekiaew
ettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrts

Chain 'B':
Sequence, based on SEQRES records:

>7a1dB (B:)
mhhhhhhenlyfqgaasmirrlsvaflstyrgpqadapgvtstgplavaahddlvsddlv
aahyrlasmrapgetkaavypgdagsgaalqivtdqapmlvdsvtvllhrhgiaytaimn
pvfrvrrgldgelldvrpaaeaapgdgadecwilvpitaaadgealteatrlvpgilaea
rqigldsgamiaalhglandlatdleghfpnaerkevaallrwladghfvllgyqqcvvg
dgnaevdpasrlgvlrlrndvlppltdsddllvlaqatmpsylrygaypyivvvrespga
srviehrfvglftvaamnanaleiplisrrveealamahrdpshpgqllrdiiqtiprpe
lfalsskqllemalavvdlgsrrrtllflradhlahfvsclvylprdryttavrlemqdi
lvrelggagidysarvsespwavvhftvrlpegtaadsvdtslenesriqdllteatrnw
gdrmisaaaaasispaalehyahafpedykqafapqdaiadisliealqddsvklvladt
aedrvwkltwylgghsaslsellpmlqsmgvvvleerpftlrrtdglpvwiyqfkisphp
siphapdaeaqrdtaqrfadavtaiwhgrveidrfnelvmragltwqqvvvlrayakylr
qagfpysqshiesvlnenphttrslidlfealfdpsqetdgrrdaqgaaaavaadidalv
sldtdrvlrafanlieatlrtnyfvarpdsararnvlafklnplvikelplprpkfeifv
ysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavknavivpvgakggfvvkr
pptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavvtppevvrrdgedayl
vvaadkgtatfsdianevaksygfwlgdafasggsigydhkamgitakgawesvkrhfre
mgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswderk
rlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppalikai
lkapvdllwnggigtyikaeteadadvgdrandqirvcgnqvrakvigeggnlgvtalgr
iefdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevg
elvladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrrada
gigltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshql
rreiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraag
dagvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlr
gddkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfal
mdhlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekia
ewettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrtsgtgttg

Sequence, based on observed residues (ATOM records):

>7a1dB (B:)
daiadisliealqddsvklvladtaedrvwkltwylgghsaslsellpmlqsmgvvvlee
rpftlrrtdglpvwiyqfkisphpsiphapdaeaqrdtaqrfadavtaiwhgrveidrfn
elvmragltwqqvvvlrayakylrqagfpysqshiesvlnenphttrslidlfealfdps
qetdgrrdaqgaaaavaadidalvsldtdrvlrafanlieatlrtnyfvnvlafklnplv
ikelplprpkfeifvysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavkna
vivpvgakggfvvkrpptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavv
tppevvrrdgedaylvvaadkgtatfsdianevaksygfwlgdafagitakgawesvkrh
fremgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswd
erkrlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppali
kailkapvdllwnggigtyikaeteadadndqirvcgnqvrakvigeggnlgvtalgrie
fdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevgel
vladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrradagi
gltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshqlrr
eiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraagda
gvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlrgd
dkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfalmd
hlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekiaew
ettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrts

Chain 'C':
Sequence, based on SEQRES records:

>7a1dC (C:)
mhhhhhhenlyfqgaasmirrlsvaflstyrgpqadapgvtstgplavaahddlvsddlv
aahyrlasmrapgetkaavypgdagsgaalqivtdqapmlvdsvtvllhrhgiaytaimn
pvfrvrrgldgelldvrpaaeaapgdgadecwilvpitaaadgealteatrlvpgilaea
rqigldsgamiaalhglandlatdleghfpnaerkevaallrwladghfvllgyqqcvvg
dgnaevdpasrlgvlrlrndvlppltdsddllvlaqatmpsylrygaypyivvvrespga
srviehrfvglftvaamnanaleiplisrrveealamahrdpshpgqllrdiiqtiprpe
lfalsskqllemalavvdlgsrrrtllflradhlahfvsclvylprdryttavrlemqdi
lvrelggagidysarvsespwavvhftvrlpegtaadsvdtslenesriqdllteatrnw
gdrmisaaaaasispaalehyahafpedykqafapqdaiadisliealqddsvklvladt
aedrvwkltwylgghsaslsellpmlqsmgvvvleerpftlrrtdglpvwiyqfkisphp
siphapdaeaqrdtaqrfadavtaiwhgrveidrfnelvmragltwqqvvvlrayakylr
qagfpysqshiesvlnenphttrslidlfealfdpsqetdgrrdaqgaaaavaadidalv
sldtdrvlrafanlieatlrtnyfvarpdsararnvlafklnplvikelplprpkfeifv
ysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavknavivpvgakggfvvkr
pptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavvtppevvrrdgedayl
vvaadkgtatfsdianevaksygfwlgdafasggsigydhkamgitakgawesvkrhfre
mgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswderk
rlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppalikai
lkapvdllwnggigtyikaeteadadvgdrandqirvcgnqvrakvigeggnlgvtalgr
iefdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevg
elvladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrrada
gigltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshql
rreiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraag
dagvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlr
gddkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfal
mdhlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekia
ewettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrtsgtgttg

Sequence, based on observed residues (ATOM records):

>7a1dC (C:)
daiadisliealqddsvklvladtaedrvwkltwylgghsaslsellpmlqsmgvvvlee
rpftlrrtdglpvwiyqfkisphpsiphapdaeaqrdtaqrfadavtaiwhgrveidrfn
elvmragltwqqvvvlrayakylrqagfpysqshiesvlnenphttrslidlfealfdps
qetdgrrdaqgaaaavaadidalvsldtdrvlrafanlieatlrtnyfvnvlafklnplv
ikelplprpkfeifvysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavkna
vivpvgakggfvvkrpptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavv
tppevvrrdgedaylvvaadkgtatfsdianevaksygfwlgdafagitakgawesvkrh
fremgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswd
erkrlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppali
kailkapvdllwnggigtyikaeteadadndqirvcgnqvrakvigeggnlgvtalgrie
fdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevgel
vladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrradagi
gltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshqlrr
eiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraagda
gvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlrgd
dkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfalmd
hlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekiaew
ettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrts

Chain 'D':
Sequence, based on SEQRES records:

>7a1dD (D:)
mhhhhhhenlyfqgaasmirrlsvaflstyrgpqadapgvtstgplavaahddlvsddlv
aahyrlasmrapgetkaavypgdagsgaalqivtdqapmlvdsvtvllhrhgiaytaimn
pvfrvrrgldgelldvrpaaeaapgdgadecwilvpitaaadgealteatrlvpgilaea
rqigldsgamiaalhglandlatdleghfpnaerkevaallrwladghfvllgyqqcvvg
dgnaevdpasrlgvlrlrndvlppltdsddllvlaqatmpsylrygaypyivvvrespga
srviehrfvglftvaamnanaleiplisrrveealamahrdpshpgqllrdiiqtiprpe
lfalsskqllemalavvdlgsrrrtllflradhlahfvsclvylprdryttavrlemqdi
lvrelggagidysarvsespwavvhftvrlpegtaadsvdtslenesriqdllteatrnw
gdrmisaaaaasispaalehyahafpedykqafapqdaiadisliealqddsvklvladt
aedrvwkltwylgghsaslsellpmlqsmgvvvleerpftlrrtdglpvwiyqfkisphp
siphapdaeaqrdtaqrfadavtaiwhgrveidrfnelvmragltwqqvvvlrayakylr
qagfpysqshiesvlnenphttrslidlfealfdpsqetdgrrdaqgaaaavaadidalv
sldtdrvlrafanlieatlrtnyfvarpdsararnvlafklnplvikelplprpkfeifv
ysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavknavivpvgakggfvvkr
pptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavvtppevvrrdgedayl
vvaadkgtatfsdianevaksygfwlgdafasggsigydhkamgitakgawesvkrhfre
mgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswderk
rlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppalikai
lkapvdllwnggigtyikaeteadadvgdrandqirvcgnqvrakvigeggnlgvtalgr
iefdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevg
elvladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrrada
gigltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshql
rreiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraag
dagvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlr
gddkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfal
mdhlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekia
ewettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrtsgtgttg

Sequence, based on observed residues (ATOM records):

>7a1dD (D:)
daiadisliealqddsvklvladtaedrvwkltwylgghsaslsellpmlqsmgvvvlee
rpftlrrtdglpvwiyqfkisphpsiphapdaeaqrdtaqrfadavtaiwhgrveidrfn
elvmragltwqqvvvlrayakylrqagfpysqshiesvlnenphttrslidlfealfdps
qetdgrrdaqgaaaavaadidalvsldtdrvlrafanlieatlrtnyfvnvlafklnplv
ikelplprpkfeifvysprvegvhlrfgfvargglrwsdrredfrteilglvkaqavkna
vivpvgakggfvvkrpptltgdaaadreatraegvecyrlfisglldvtdnvdkatgavv
tppevvrrdgedaylvvaadkgtatfsdianevaksygfwlgdafagitakgawesvkrh
fremgvdtqtqdftvvgigdmsgdvfgngmllskhirlvaafdhrdifldpnpdagrswd
erkrlfdlprsswadydkslisegggvysrqqksipispqvrtalgldadveeltppali
kailkapvdllwnggigtyikaeteadadndqirvcgnqvrakvigeggnlgvtalgrie
fdlaggrintdaldnsagvdcsdhevnikilidsavtagkvtpeertelllsmtdevgel
vladnrdqndlmgtsranaasllsvharmikdlvdnrglnrelealpsekeirrradagi
gltspelatlmahvklalkddvlasdlpdqevfasrlpyyfptrlreelhgeirshqlrr
eiittmlvndlvdtagisyayritedvgvgpvdavrsyvainaifgigdvwrriraagda
gvptsvtdrmtldlrrlvdragrwllnyrpqplavgaeinrfgakvaaltprmsewlrgd
dkaivskeagdfashgvpedlayhiatglyqyslldvidiadivdrepdevadtyfalmd
hlgadalltavsrlsrddrwhslarlairddiygslralcfdvlavgepdengeekiaew
ettnssrvtrarrtlteiykdgeqdlatlsvaarqirsmtrts