PDB entry 6zu4

View 6zu4 on RCSB PDB site
Description: human sirt6 13-308 in complex with adp-ribose and the activator fluvastatin
Deposited on 2020-07-21, released 2020-11-18
The last revision was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N6T7 (6-End)
      • expression tag (3-5)
  • Chain 'B':
    Compound: nad-dependent protein deacetylase sirtuin-6
    Species: Homo sapiens [TaxId:9606]
    Gene: SIRT6, SIR2L6
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 115, AR6, ZN, GOL, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6zu4A (A:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6zu4A (A:)
pftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphg
vwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdkl
aelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrd
laladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihg
yvdevmtrlmkhlgleipawdgprvleralpplprpptpkle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6zu4B (B:)
gidpftadkgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrg
phgvwtmeerglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfpr
dklaelhgnmfveecakcktqyvrdtvvgtmglkatgrlctvakarglracrgelrdtil
dwedslpdrdlaladeasrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkh
drhadlrihgyvdevmtrlmkhlgleipawdgprvleralpplprpptpklepkeesptr
in

    Sequence, based on observed residues (ATOM records):
    >6zu4B (B:)
kgkcglpeifdppeelerkvwelarlvwqsssvvfhtgagistasgipdfrgphgvwtme
erglapkfdttfesarptqthmalvqlervgllrflvsqnvdglhvrsgfprdklaelhg
nmfveecakcktqyvrdtvvgtmglkatgrlctvacrgelrdtildwedslpdrdlalad
easrnadlsitlgtslqirpsgnlplatkrrggrlvivnlqptkhdrhadlrihgyvdev
mtrlmkhlgleipawdgprvleralpplprpptpkle