PDB entry 6zsj

View 6zsj on RCSB PDB site
Description: The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members.
Class: endocytosis
Keywords: Rab GTPase, EHBP1, bMERB domain, CH domain, ENDOCYTOSIS
Deposited on 2020-07-15, released 2020-09-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-14, with a file datestamp of 2020-10-09.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zsja_
  • Chain 'B':
    Compound: Ras-related protein Rab-8A
    Species: Homo sapiens [TaxId:9606]
    Gene: Rab8a, Mel, Rab8
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zsjb_
  • Chain 'C':
    Compound: EH domain-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: EHBP1, KIAA0903, NACSIN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NDI1
      • engineered mutation (63)
  • Chain 'D':
    Compound: EH domain-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: EHBP1, KIAA0903, NACSIN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NDI1
      • engineered mutation (63)
  • Heterogens: GNP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zsjA (A:)
ghmaktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkrik
lqiwdtagqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmi
lgnkcdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6zsjA (A:)
tydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiwd
tagqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnkc
dvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zsjB (B:)
ghmaktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkrik
lqiwdtagqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmi
lgnkcdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdkk

    Sequence, based on observed residues (ATOM records): (download) 
    >6zsjB (B:)
ktydylfkllligdsgvgktcvlfrfsedafnstfistigidfkirtieldgkriklqiw
dtagqerfrtittayyrgamgimlvyditneksfdnirnwirnieehasadvekmilgnk
cdvndkrqvskergeklaldygikfmetsakaninvenafftlardikakmdk

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.