PDB entry 6zr5

View 6zr5 on RCSB PDB site
Description: Crystal structure of JNK1 in complex with ATF2(19-58)
Class: transcription
Keywords: transcription, mapk signaling pathways
Deposited on 2020-07-10, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-11-25, with a file datestamp of 2020-11-20.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK8, JNK1, PRKM8, SAPK1, SAPK1C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zr5a_
  • Chain 'B':
    Compound: Mitogen-activated protein kinase 8
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK8, JNK1, PRKM8, SAPK1, SAPK1C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zr5b_
  • Chain 'C':
    Compound: Cyclic AMP-dependent transcription factor ATF-2
    Species: Homo sapiens [TaxId:9606]
    Gene: ATF2, CREB2, CREBP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15336
      • engineered mutation (15)
      • engineered mutation (28)
    Domains in SCOPe 2.08: d6zr5c_
  • Chain 'D':
    Compound: Cyclic AMP-dependent transcription factor ATF-2
    Species: Homo sapiens [TaxId:9606]
    Gene: ATF2, CREB2, CREBP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15336 (1-End)
      • expression tag (0)
      • engineered mutation (15)
      • engineered mutation (28)
    Domains in SCOPe 2.08: d6zr5d1, d6zr5d2
  • Heterogens: MG, ANP, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zr5A (A:)
gsmsrskrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikkls
rpfqnqthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqv
iqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagt
sfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemikggvlfpgtdhidqwnkvi
eqlgtpcpefmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardll
skmlvidaskrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkeliyk
evmdle

    Sequence, based on observed residues (ATOM records): (download) 
    >6zr5A (A:)
rskrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfq
nqthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqme
ldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglarttryyrap
evilgmgykenvdiwsvgcimgemikggvlfpgtdhidqwnkvieqlgtpcpefmkklqp
tvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllskmlvidaskrisvde
alqhpyinvwydpseaeapppkipdkqlderehtieewkeliykevmd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zr5B (B:)
gsmsrskrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikkls
rpfqnqthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqv
iqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagt
sfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemikggvlfpgtdhidqwnkvi
eqlgtpcpefmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardll
skmlvidaskrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkeliyk
evmdle

    Sequence, based on observed residues (ATOM records): (download) 
    >6zr5B (B:)
skrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfqn
qthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmel
dhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsfmmt
pyvvtryyrapevilgmgykenvdiwsvgcimgemikggvlfpgtdhidqwnkvieqlgt
pcpefmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllskmlv
idaskrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkeliykevmd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6zr5C (C:)
ysddkpflctapgcgrrftnedhlavhkrkhemtlkfgpa

    Sequence, based on observed residues (ATOM records): (download) 
    >6zr5C (C:)
dkpflctapgcgrrftnedhlavhkrkhemtlkfgp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6zr5D (D:)
ysddkpflctapgcgrrftnedhlavhkrkhemtlkfgpa

    Sequence, based on observed residues (ATOM records): (download) 
    >6zr5D (D:)
ysddkpflctapgcgrrftnedhlavhkrkhemtlkfg