PDB entry 6zpu

View 6zpu on RCSB PDB site
Description: Crystal structure of Angiotensin-1 converting enzyme C-domain with inserted symmetry molecule C-terminus.
Class: hydrolase
Keywords: Angiotensin-1 converting enzyme, C-terminus insertion, metalloprotease, HYDROLASE
Deposited on 2020-07-09, released 2020-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiotensin-converting enzyme
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE, DCP, DCP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12821 (Start-596)
      • engineered mutation (27)
      • engineered mutation (53)
      • engineered mutation (118)
      • engineered mutation (300)
      • engineered mutation (549)
    Domains in SCOPe 2.08: d6zpua_
  • Heterogens: ACT, EDO, ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zpuA (A:)
lvtdeaeaskfveeydrtsqvvwneyaganwnyntnittetskillqknmqiaqhtlkyg
tqarkfdvnqlqnttikriikkvqdleraalpaqeleeynkilldmettysvatvchpqg
sclqlepdltnvmatsrkyedllwawegwrdkagrailqfypkyvelinqaarlngyvda
gdswrsmyetpsleqdlerlfqelqplylnlhayvrralhrhygaqhinlegpipahllg
nmwaqtwsniydlvvpfpsapsmdtteamlkqgwtprrmfkeaddfftslgllpvppefw
qksmlekptdgrevvchasawdfyngkdfrikqcttvnledlvvahhemghiqyfmqykd
lpvalreganpgfheaigdvlalsvstpkhlhslnllsseggsdehdinflmkmaldkia
fipfsylvdqwrwrvfdgsitkenynqewwslrlkyqglcppvprtqgdfdpgakfhips
svpyiryfvsfiiqfqfhealcqaaghtgplhkcdiyqskeagqrlatamklgfsrpwpe
amqlitgqpqmsasamlsyfkplldwlrtenelhgeklgwpqynwtpnsarsegplp

    Sequence, based on observed residues (ATOM records): (download) 
    >6zpuA (A:)
eaeaskfveeydrtsqvvwneyaganwnyntnittetskillqknmqiaqhtlkygtqar
kfdvnqlqnttikriikkvqdleraalpaqeleeynkilldmettysvatvchpqgsclq
lepdltnvmatsrkyedllwawegwrdkagrailqfypkyvelinqaarlngyvdagdsw
rsmyetpsleqdlerlfqelqplylnlhayvrralhrhygaqhinlegpipahllgnmwa
qtwsniydlvvpfdtteamlkqgwtprrmfkeaddfftslgllpvppefwqksmlekptd
grevvchasawdfyngkdfrikqcttvnledlvvahhemghiqyfmqykdlpvalregan
pgfheaigdvlalsvstpkhlhslnllsseggsdehdinflmkmaldkiafipfsylvdq
wrwrvfdgsitkenynqewwslrlkyqglcppvprtqgdfdpgakfhipssvpyiryfvs
fiiqfqfhealcqaaghtgplhkcdiyqskeagqrlatamklgfsrpwpeamqlitgqpq
msasamlsyfkplldwlrtenelhgeklgwpqynwtpnsarsegplp