PDB entry 6zor

View 6zor on RCSB PDB site
Description: Oestrogen receptor ligand binding domain in complex with compound 28
Class: gene regulation
Keywords: oestrogen receptor, GENE REGULATION
Deposited on 2020-07-07, released 2021-01-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372 (4-End)
      • expression tag (0-3)
      • engineered mutation (78)
      • engineered mutation (114)
      • engineered mutation (233)
    Domains in SCOPe 2.07: d6zora1, d6zora2
  • Chain 'B':
    Compound: Estrogen receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, ESR, NR3A1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03372 (4-End)
      • expression tag (3)
      • engineered mutation (78)
      • engineered mutation (114)
      • engineered mutation (233)
    Domains in SCOPe 2.07: d6zorb1, d6zorb2
  • Heterogens: QNH, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zorA (A:)
gshmalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldki
tdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydllle
mldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >6zorA (A:)
gshmalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytleekdhihrvldkitdtlihlm
akagltlqqqhqrlaqlllilshirhmsnkgmehlysmvvpsydlllemldahrlhap

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zorB (B:)
gshmalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwak
rvpgfvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmv
eifdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldki
tdtlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydllle
mldahrlhapts

    Sequence, based on observed residues (ATOM records): (download) 
    >6zorB (B:)
malsltadqmvsalldaeppilyseypfseasmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlmakaglt
lqqqhqrlaqlllilshirhmsnkgmehlysmvvpsydlllemldah