PDB entry 6zn5

View 6zn5 on RCSB PDB site
Description: sars-cov-2 nsp1 bound to a pre-40s-like ribosome complex - state 2
Deposited on 2020-07-06, released 2020-07-29
The last revision was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '2':
    Compound: 18S Ribosomal RNA
    Species: Homo sapiens [TaxId:9606]
  • Chain 'B':
    Compound: 40S Ribosomal protein SA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 40s ribosomal protein s3a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 40S ribosomal protein S2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 40S ribosomal protein S4, X isoform
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: 40S ribosomal protein S3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: 40s ribosomal protein s6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: 40S ribosomal protein S7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: 40s ribosomal protein s8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: 40S ribosomal protein S9
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: 40S ribosomal protein S5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: 40S ribosomal protein S11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: 40S ribosomal protein S10
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: 40S ribosomal protein S13
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: 40s ribosomal protein s12
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: 40s ribosomal protein s14
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: 40S ribosomal protein S15
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: 40S ribosomal protein S16
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: 40S ribosomal protein S17
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: 40S ribosomal protein S18
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'U':
    Compound: 40S ribosomal protein S19
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'V':
    Compound: 40S ribosomal protein S20
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: 40S ribosomal protein S15a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: 40S ribosomal protein S23
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Y':
    Compound: 40S ribosomal protein S24
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Z':
    Compound: 40S ribosomal protein S21
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'a':
    Compound: 40S ribosomal protein S25
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'b':
    Compound: 40S ribosomal protein S27
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'c':
    Compound: 40S ribosomal protein S26
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'd':
    Compound: 40S ribosomal protein S28
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'e':
    Compound: 40S ribosomal protein S30
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'f':
    Compound: 40S ribosomal protein S29
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'g':
    Compound: Ribosomal protein S27a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'i':
    Compound: Non-structural protein 1
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Database cross-references and differences (RAF-indexed):
  • Chain 'j':
    Compound: Receptor of activated protein C kinase 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'u':
    Compound: Pre-rRNA-processing protein TSR1 homolog
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain '2':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5B (B:)
    sgaldvlqmkeedvlkflaagthlggtnldfqmeqyiykrksdgiyiinlkrtwekllla
    araivaienpadvsvissrntgqravlkfaaatgatpiagrftpgtftnqiqaafreprl
    lvvtdpradhqplteasyvnlptialcntdsplryvdiaipcnnkgahsvglmwwmlare
    vlrmrgtisrehpwevmpdlyfyrdp
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5C (C:)
    vvdpfskkdwydvkapamfnirnigktlvtrtqgtkiasdglkgrvfevsladlqndeva
    frkfklitedvqgkncltnfhgmdltrdkmcsmvkkwqtmieahvdvkttdgyllrlfcv
    gftkkrnnqirktsyaqhqqvrqirkkmmeimtrevqtndlkevvnklipdsigkdieka
    cqsiyplhdvfvrkvkmlkkpkfelgklmelhg
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5D (D:)
    ewmpvtklgrlvkdmkiksleeiylfslpikeseiidfflgaslkdevlkimpvqkqtra
    gqrtrfkafvaigdynghvglgvkcskevatairgaiilaklsivpvrrgywgnkigkph
    tvpckvtgrcgsvlvrlipaprgtgivsapvpkkllmmagiddcytsargctatlgnfak
    atfdaisktysyltpdlwketvftkspyqeftdhlvkt
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5E (E:)
    argpkkhlkrvaapkhwmldkltgvfaprpstgphklreclpliiflrnrlkyaltgdev
    kkicmqrfikidgkvrtditypagfmdvisidktgenfrliydtkgrfavhritpeeaky
    klckvrkifvgtkgiphlvthdartirypdplikvndtiqidletgkitdfikfdtgnlc
    mvtgganlgrigvitnrerhpgsfdvvhvkdangnsfatrlsnifvigkgnkpwislprg
    kgirltiaeerdkrlaakqssg
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5F (F:)
    vqiskkrkfvadgifkaelnefltrelaedgysgvevrvtptrteiiilatrtqnvlgek
    grrireltavvqkrfgfpegsvelyaekvatrglcaiaqaeslrykllgglavrracygv
    lrfimesgakgcevvvsgklrgqraksmkfvdglmihsgdpvnyyvdtavrhvllrqgvl
    gikvkimlpwdptgkigpkkplpdhvsivepkdeilpttpiseqk
    

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5G (G:)
    mklnisfpatgcqklievdderklrtfyekrmatevaadalgeewkgyvvrisggndkqg
    fpmkqgvlthgrvrlllskghscyrprrtgerkrksvrgcivdanlsvlnlvivkkgekd
    ipgltdttvprrlgpkrasrirklfnlskeddvrqyvvrkplnkegkkprtkapkiqrlv
    tprvlqhkrrrialkkqrtkknkeeaaeyakllakrmkeakekrqeqiak
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5H (H:)
    ivkpngekpdefesgisqallelemnsdlkaqlrelnitaakeievgggrkaiiifvpvp
    qlksfqkiqvrlvrelekkfsgkhvvfiaqrrilpkptrksrtknkqkrprsrtltavhd
    ailedlvfpseivgkrirvkldgsrlikvhldkaqqnnvehkvetfsgvykkltgkdvnf
    efpefq
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5I (I:)
    gisrdnwhkrrktggkrkpyhkkrkyelgrpaantkigprrihtvrvrggnkkyralrld
    vgnfswgsecctrktriidvvynasnnelvrtktlvkncivlidstpyrqwyeshyalpl
    grkkgakltpeeeeilnkkrskkiqkkyderkknakisslleeqfqqgkllaciasrpgq
    cgradgyvlegkelefylrkikark
    

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5J (J:)
    pvarswvcrktyvtprrpfeksrldqelkligeyglrnkrevwrvkftlakirkaarell
    tldekdprrlfegnallrrlvrigvldegkmkldyilglkiedflerrlqtqvfklglak
    sihharvlirqrhirvrkqvvnipsfivrldsqkhidfslrspygggrpgrvkrknakkg
    

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5K (K:)
    diklfgkwstddvqindislqdyiavkekyakylphsagryaakrfrkaqcpiverltns
    mmmhgrnngkklmtvrivkhafeiihlltgenplqvlvnaiinsgpredstrigragtvr
    rqavdvsplrrvnqaiwllctgareaafrniktiaecladelinaakgssnsyaikkkde
    lervaksnr
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5L (L:)
    adiqterayqkqptifqnkkrvllgetgkeklpryykniglgfktpkeaiegtyidkkcp
    ftgnvsirgrilsgvvtkmkmqrtivirrdylhyirkynrfekrhknmsvhlspcfrdvq
    igdivtvgecrplsktvrfnvlkvtkaagtk
    

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5M (M:)
    mpkknriaiyellfkegvmvakkdvhmpkhpeladknvpnlhvmkamqslksrgyvkeqf
    awrhfywyltnegiqylrdylhlppeivpatlrrs
    

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5N (N:)
    grmhapgkglsqsalpyrrsvptwlkltsddvkeqiyklakkgltpsqigvilrdshgva
    qvrfvtgnkilrilkskglapdlpedlyhlikkavavrkhlernrkdkdakfrliliesr
    ihrlaryyktkrvlppnwkyesstasalv
    

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5O (O:)
    gvmdvntalqevlktalihdglargireaakaldkrqahlcvlasncdepmyvklvealc
    aehqinlikvddnkklgewvglckidregkprkvvgcscvvvkdygkesqakdvieeyfk
    ckk
    

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5P (P:)
    lgpqvaegenvfgvchifasfndtfvhvtdlsgketicrvtggmkvkadrdesspyaaml
    aaqdvaqrckelgitalhiklratggnrtktpgpgaqsalralarsgmkigriedvtpip
    sdstrrkggrrgrrl
    

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5Q (Q:)
    ftyrgvdldqlldmsyeqlmqlysarqrrrlnrglrrkqhsllkrlrkakkeappmekpe
    vvkthlrdmiilpemvgsmvgvyngktfnqveikpemighylgefsitykpvkhgrpgig
    

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5R (R:)
    qsvqvfgrkktatavahckrgnglikvngrplemieprtlqykllepvlllgkerfagvd
    irvrvkggghvaqiyairqsiskalvayyqkyvdeaskkeikdiliqydrtllvadprrc
    eskkfggpgararyqksyr
    

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5S (S:)
    grvrtktvkkaarviiekyytrlgndfhtnkrvceeiaiipskklrnkiagyvthlmkri
    qrgpvrgisiklqeeererrdnyvpevsaldqeiievdpdtkemlklldfgslsnlqvtq
    ptvgmnfktprg
    

  • Chain 'T':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5T (T:)
    lvipekfqhilrvlntnidgrrkiafaitaikgvgrryahvvlrkadidltkragelted
    evervitimqnprqykipdwflnrqkdvkdgkysqvlangldnklredlerlkkirahrg
    lrhfwglrvrgqhtkttgrrgrt
    

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5U (U:)
    pgvtvkdvnqqefvralaaflkksgklkvpewvdtvklakhkelapydenwfytraasta
    rhlylrggagvgsmtkiyggrqrngvmpshfsrgsksvarrvlqaleglkmvekdqdggr
    kltpqgqrdldriagqvaaankkh
    

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5V (V:)
    ihriritltsrnvkslekvcadlirgakeknlkvkgpvrmptktlrittrktpcgegskt
    wdrfqmrihkrlidlhspseivkqitsisiepgvevevtia
    

  • Chain 'W':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5W (W:)
    vrmnvladalksinnaekrgkrqvlirpcskvivrfltvmmkhgyigefeiiddhragki
    vvnltgrlnkcgvisprfdvqlkdlekwqnnllpsrqfgfivlttsagimdheearrkht
    ggkilgfff
    

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5X (X:)
    gkcrglrtarklrshrrdqkwhdkqykkahlgtalkanpfggashakgivlekvgveakq
    pnsairkcvrvqlikngkkitafvpndgclnfieendevlvagfgrkghavgdipgvrfk
    vvkvanvsllalykgkkerpr
    

  • Chain 'Y':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5Y (Y:)
    dtvtirtrkfmtnrllqrkqmvidvlhpgkatvpkteireklakmykttpdvifvfgfrt
    hfgggkttgfgmiydsldyakknepkhrlarhglyekkktsrkqrkerknrmkkvrgtak
    anvg
    

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5Z (Z:)
    mqndagefvdlyvprkcsasnriigakdhasiqmnvaevdkvtgrfngqfktyaicgair
    rmgesddsilrlakadgivskn
    

  • Chain 'a':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5a (a:)
    dklnnlvlfdkatydklckevpnyklitpavvserlkirgslaraalqellskgliklvs
    khraqviytrnt
    

  • Chain 'b':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5b (b:)
    plakdllhpspeeekrkhkkkrlvqspnsyfmdvkcpgcykittvfshaqtvvlcvgcst
    vlcqptggkarltegcsfrrkq
    

  • Chain 'c':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5c (c:)
    tkkrrnngrakkgrghvqpirctncarcvpkdkaikkfvirniveaaavrdiseasvfda
    yvlpklyvklhycvscaihskvvrnrsrearkdrtppprfr
    

  • Chain 'd':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5d (d:)
    piklarvtkvlgrtgsqgqctqvrvefmddtsrsiirnvkgpvregdvltlleserearr
    l
    

  • Chain 'e':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5e (e:)
    gslaragkvrgqtpkvakqekkkkktgrakrrmqynrrfvnvvptfgkkkgpnans
    

  • Chain 'f':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5f (f:)
    hqqlywshprkfgqgsrscrvcsnrhglirkyglnmcrqcfrqyakdigfikld
    

  • Chain 'g':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5g (g:)
    kkrkkkscttpkknkhkrkkvklavlkyykvdengkisrlrrecpsdecgagvfmashfd
    rhycgkccltyc
    

  • Chain 'i':
    Sequence, based on SEQRES records:
    >6zn5i (i:)
    meslvpgfnekthvqlslpvlqvrdvlvrgfgdsveevlsearqhlkdgtcglvevekgv
    lpqleqpyvfikrsdartaphghvmvelvaelegiqygrsgetlgvlvphvgeipvayrk
    vllrkngnkgagghsygadlksfdlgdelgtdpyedfqenwntkhssgvtrelmrelngg
    

    Sequence, based on observed residues (ATOM records):
    >6zn5i (i:)
    dpyedfqenwntkhssgvtrelmrelngg
    

  • Chain 'j':
    Sequence; same for both SEQRES and ATOM records:
    >6zn5j (j:)
    teqmtlrgtlkghngwvtqiattpqfpdmilsasrdktiimwkltrdetnygipqralrg
    hshfvsdvvissdgqfalsgswdgtlrlwdlttgtttrrfvghtkdvlsvafssdnrqiv
    sgsrdktiklwntlgvckytvqdeshsewvscvrfspnssnpiivscgwdklvkvwnlan
    cklktnhightgylntvtvspdgslcasggkdgqamlwdlnegkhlytldggdiinalcf
    spnrywlcaatgpsikiwdlegkiivdelkqevistsskaeppqctslawsadgqtlfag
    ytdnlvrvwqvtig
    

  • Chain 'u':
    Sequence, based on SEQRES records:
    >6zn5u (u:)
    maahrpgplkqqnkahkggrhrgrgsaqrdgkgrlalktlskkvrkelsrvdqrhrasql
    rkqkkeavlaekrqlggkdgpphqvlvvplhsrislpeamqllqdrdtgtvhlnelgntq
    nfmllcprlkhrwfftsarpgdlhvvldmakvadtilflldplegwdstgdyclsclfaq
    glptytlavqgisglplkkqidtrkklskavekrfphdklllldtqqeagmllrqlanqk
    qqhlafrdrraylfahavdfvpseennlvgtlkisgyvrgqtlnvnrllhivgygdfqmk
    qidapgdpfplnprgikpqkdpdmameicatdavddmeeglkvlmkadpgrqeslqaevi
    pdpmegeqtwpteeelseakdflkesskvvkkvpkgtssyqaewildggsqsggegdeye
    yddmehedfmeeesqdesseeeeeyetmtigesvhddlydkkvdeeaeakmlekykqerl
    eemfpdevdtprdvaarirfqkyrglksfrtspwdpkenlpqdyarifqfqnftntrksi
    fkeveekevegaevgwyvtlhvsevpvsvvecfrqgtpliafsllpheqkmsvlnmvvrr
    dpgntepvkakeelifhcgfrrfrasplfsqhtaadkhklqrfltadmalvatvyapitf
    ppasvllfkqksngmhsliatghlmsvdpdrmvikrvvlsghpfkiftkmavvrymffnr
    edvlwfkpvelrtkwgrrghikeplgthghmkcsfdgklksqdtvlmnlykrvfpkwtyd
    pyvpepvpwlkseisstvpqggme
    

    Sequence, based on observed residues (ATOM records):
    >6zn5u (u:)
    elsrvdqrhrasqlrkqkkeavlaekrqlggkdgpphqvlvvplhsrislpeamqllqdg
    tvhlnelgntqnfmllcprlkhrwfftsarpgdlhvvldmakvadtilflldplegwdst
    gdyclsclfaqglptytlavqgisglplkkqidtrkklskavekrfphdklllldtqqea
    gmllrqlanqkqqhlafrdrraylfahavdfvpseennlvgtlkisgyvrgqtlnvnrll
    hivgygdfqmkqidapgdpfplnpkvlmkadpgrqeslqaevipdpdeeaeakmlekykq
    erleemfpdevdtprdvaarirfqkyrglksfrtspwdpkenlpqdyarifqfqnftntr
    ksifkeveekevegaevgwyvtlhvsevpvsvvecfrqgtpliafsllpheqkmsvlnmv
    vrrdpgntepvkakeelifhcgfrrfrasplfsqhtaadkhklqrfltadmalvatvyap
    itfppasvllfkqksngmhsliatghlmsvdpdrmvikrvvlsghpfkiftkmavvrymf
    fnredvlwfkpvelrtkwgrrghikeplgthghmkcsfdgklksqdtvlmnlykrvfpkw
    tydpyvpepvpwlks