PDB entry 6zf5

View 6zf5 on RCSB PDB site
Description: Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein interaction
Class: peptide binding protein
Keywords: Keap1, Nrf2, Oxidative stress, Small molecule complex, PEPTIDE BINDING PROTEIN
Deposited on 2020-06-16, released 2021-04-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 1.29 Å
R-factor: N/A
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Mus musculus [TaxId:10090]
    Gene: Keap1, Inrf2, Kiaa0132
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zf5a_
  • Heterogens: QH8, SO4, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zf5A (A:)
gpkvgrliytaggyfrqslsyleaynpsngswlrladlqvprsglagcvvggllyavggr
nnspdgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiyavggshgcihhssv
eryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmi
tpmntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmrhhrsalgit
vhqgkiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgvavtmepcrkqidqq
nctc

    Sequence, based on observed residues (ATOM records): (download) 
    >6zf5A (A:)
vgrliytaggyfrqslsyleaynpsngswlrladlqvprsglagcvvggllyavggrnns
pdgntdssaldcynpmtnqwspcasmsvprnrigvgvidghiyavggshgcihhssvery
eperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitpm
ntirsgagvcvlhnciyaaggydgqdqlnsverydvetetwtfvapmrhhrsalgitvhq
gkiyvlggydghtfldsvecydpdsdtwsevtrmtsgrsgvgvavtmep