PDB entry 6zdf

View 6zdf on RCSB PDB site
Description: Structure of the catalytic domain of human endo-alpha-mannosidase MANEA in complex with HEPES
Class: hydrolase
Keywords: Golgi, hydrolase, mannosidase, retaining
Deposited on 2020-06-14, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycoprotein endo-alpha-1,2-mannosidase
    Species: Homo sapiens [TaxId:9606]
    Gene: MANEA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zdfa_
  • Chain 'B':
    Compound: Glycoprotein endo-alpha-1,2-mannosidase
    Species: Homo sapiens [TaxId:9606]
    Gene: MANEA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6zdfb_
  • Chain 'C':
    Compound: Glycoprotein endo-alpha-1,2-mannosidase
    Species: Homo sapiens [TaxId:9606]
    Gene: MANEA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SRI9 (17-End)
      • expression tag (16)
    Domains in SCOPe 2.08: d6zdfc1, d6zdfc2
  • Heterogens: EPE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zdfA (A:)
mnhkvhhhhhhiegrhmplnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknyp
qgrhnppddigssfypelgsyssrdpsviethmrqmrsasigvlalswyppdvndengep
tdnlvptildkahkynlkvtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgn
alpmfyvydsyitkpekwanllttsgsrsirnspydglfiallveekhkydilqsgfdgi
ytyfatngftygsshqnwaslklfcdkynlifipsvgpgyidtsirpwntqntrnringk
yyeiglsaalqtrpslisitsfnewhegtqiekavpkrtsntvyldyrphkpglyleltr
kwsekyskeratyaldrqlpvs

    Sequence, based on observed residues (ATOM records): (download) 
    >6zdfA (A:)
lnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknypqgrhnppddigssfypel
gsyssrdpsviethmrqmrsasigvlalswyppdvndengeptdnlvptildkahkynlk
vtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgnalpmfyvydsyitkpekw
anllttsgsrsirnspydglfiallveekhkydilqsgfdgiytyfatngftygsshqnw
aslklfcdkynlifipsvgpgyidtsirpwntqntrnringkyyeiglsaalqtrpslis
itsfnewhegtqiekavpkrtsntvyldyrphkpglyleltrkwsekyskeratya

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zdfB (B:)
mnhkvhhhhhhiegrhmplnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknyp
qgrhnppddigssfypelgsyssrdpsviethmrqmrsasigvlalswyppdvndengep
tdnlvptildkahkynlkvtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgn
alpmfyvydsyitkpekwanllttsgsrsirnspydglfiallveekhkydilqsgfdgi
ytyfatngftygsshqnwaslklfcdkynlifipsvgpgyidtsirpwntqntrnringk
yyeiglsaalqtrpslisitsfnewhegtqiekavpkrtsntvyldyrphkpglyleltr
kwsekyskeratyaldrqlpvs

    Sequence, based on observed residues (ATOM records): (download) 
    >6zdfB (B:)
plnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknypqgrhnppddigssfype
lgsyssrdpsviethmrqmrsasigvlalswyppdvndengeptdnlvptildkahkynl
kvtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgnalpmfyvydsyitkpek
wanllttsgsrsirnspydglfiallveekhkydilqsgfdgiytyfatngftygsshqn
waslklfcdkynlifipsvgpgyidtsirpwntqntrnringkyyeiglsaalqtrpsli
sitsfnewhegtqiekavpkrtsntvyldyrphkpglyleltrkwsekyskeratya

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6zdfC (C:)
mnhkvhhhhhhiegrhmplnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknyp
qgrhnppddigssfypelgsyssrdpsviethmrqmrsasigvlalswyppdvndengep
tdnlvptildkahkynlkvtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgn
alpmfyvydsyitkpekwanllttsgsrsirnspydglfiallveekhkydilqsgfdgi
ytyfatngftygsshqnwaslklfcdkynlifipsvgpgyidtsirpwntqntrnringk
yyeiglsaalqtrpslisitsfnewhegtqiekavpkrtsntvyldyrphkpglyleltr
kwsekyskeratyaldrqlpvs

    Sequence, based on observed residues (ATOM records): (download) 
    >6zdfC (C:)
mplnnylhvfyyswygnpqfdgkyihwnhpvlehwdpriaknypqgrhnppddigssfyp
elgsyssrdpsviethmrqmrsasigvlalswyppdvndengeptdnlvptildkahkyn
lkvtfhiepysnrddqnmyknvkyiidkygnhpafyryktktgnalpmfyvydsyitkpe
kwanllttsgsrsirnspydglfiallveekhkydilqsgfdgiytyfatngftygsshq
nwaslklfcdkynlifipsvgpgyidtsirpwntqntrnringkyyeiglsaalqtrpsl
isitsfnewhegtqiekavpkrtsntvyldyrphkpglyleltrkwsekyskeratya