PDB entry 6zd3

View 6zd3 on RCSB PDB site
Description: Crystal structure of YTHDC1 M438A mutant
Class: RNA binding protein
Keywords: YTHDC1, m6A, complex, inhibitor, RNA BINDING PROTEIN
Deposited on 2020-06-13, released 2021-01-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-31, with a file datestamp of 2021-03-26.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: YTH domain containing 1
    Species: Homo sapiens [TaxId:9606]
    Gene: YTHDC1
    Database cross-references and differences (RAF-indexed):
    • PDB 6ZD3
    Domains in SCOPe 2.08: d6zd3a1, d6zd3a2
  • Chain 'B':
    Compound: YTH domain containing 1
    Species: Homo sapiens [TaxId:9606]
    Gene: YTHDC1
    Database cross-references and differences (RAF-indexed):
    • PDB 6ZD3
    Domains in SCOPe 2.08: d6zd3b1, d6zd3b2
  • Heterogens: SO4, PEG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zd3A (A:)
mhhhhhhssgrenlyfqgtsklkyvlqdarffliksnnhenvslakakgvwstlpvnekk
lnlafrsarsvilifsvresgkfqgfarlsseshhggspihwvlpagmsakalggvfkid
wicrrelpftksahltnpwnehkpvkigrdgqeielecgtqlcllfppdesidlyqvihk
mrh

    Sequence, based on observed residues (ATOM records): (download) 
    >6zd3A (A:)
gtsklkyvlqdarffliksnnhenvslakakgvwstlpvnekklnlafrsarsvilifsv
resgkfqgfarlsseshhggspihwvlggvfkidwicrrelpftksahltnpwnehkpvk
igrdgqeielecgtqlcllfppdesidlyqvihkm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6zd3B (B:)
mhhhhhhssgrenlyfqgtsklkyvlqdarffliksnnhenvslakakgvwstlpvnekk
lnlafrsarsvilifsvresgkfqgfarlsseshhggspihwvlpagmsakalggvfkid
wicrrelpftksahltnpwnehkpvkigrdgqeielecgtqlcllfppdesidlyqvihk
mrh

    Sequence, based on observed residues (ATOM records): (download) 
    >6zd3B (B:)
gtsklkyvlqdarffliksnnhenvslakakgvwstlpvnekklnlafrsarsvilifsv
resgkfqgfarlsseshhggspihwvlpggvfkidwicrrelpftksahltnpwnehkpv
kigrdgqeielecgtqlcllfppdesidlyqvihkmr