PDB entry 6z7z

View 6z7z on RCSB PDB site
Description: Porcine insulin in complex with the analytical antibody OXI-005 Fab
Class: hormone
Keywords: complex, insulin, analytical antibody, Fab, HORMONE
Deposited on 2020-06-02, released 2020-12-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: OXI-005 Fab Light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Z (0-End)
    Domains in SCOPe 2.08: d6z7za1, d6z7za2
  • Chain 'B':
    Compound: OXI-005 Fab Heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Z (0-End)
    Domains in SCOPe 2.08: d6z7zb_
  • Chain 'C':
    Compound: OXI-005 Fab Light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Z (0-End)
    Domains in SCOPe 2.08: d6z7zc1, d6z7zc2
  • Chain 'D':
    Compound: OXI-005 Fab Heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Z (0-End)
    Domains in SCOPe 2.08: d6z7zd_
  • Chain 'E':
    Compound: insulin
    Species: Sus scrofa [TaxId:9823]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: insulin
    Species: Sus scrofa [TaxId:9823]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: insulin
    Species: Sus scrofa [TaxId:9823]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: insulin
    Species: Sus scrofa [TaxId:9823]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6z7zA (A:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7zA (A:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6z7zB (B:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7zB (B:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6z7zC (C:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7zC (C:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6z7zD (D:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7zD (D:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprd

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.