PDB entry 6z7y

View 6z7y on RCSB PDB site
Description: Human insulin in complex with the analytical antibody OXI-005 Fab
Class: hormone
Keywords: complex, insulin, analytical antibody, Fab, HORMONE
Deposited on 2020-06-02, released 2020-12-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: OXI-005 Fab Light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Y (0-212)
    Domains in SCOPe 2.08: d6z7ya1, d6z7ya2
  • Chain 'B':
    Compound: OXI-005 Fab Heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Y (0-End)
    Domains in SCOPe 2.08: d6z7yb_
  • Chain 'C':
    Compound: OXI-005 Fab Light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Y (0-End)
    Domains in SCOPe 2.08: d6z7yc1, d6z7yc2
  • Chain 'D':
    Compound: OXI-005 Fab Heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6Z7Y (0-End)
    Domains in SCOPe 2.08: d6z7yd_
  • Chain 'E':
    Compound: insulin
    Species: Homo sapiens [TaxId:9606]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: insulin
    Species: Homo sapiens [TaxId:9606]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: insulin
    Species: Homo sapiens [TaxId:9606]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: insulin
    Species: Homo sapiens [TaxId:9606]
    Gene: INS
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6z7yA (A:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6z7yB (B:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7yB (B:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvt
vpsstwpsetvtcnvahpasstkvdkkivpr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6z7yC (C:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7yC (C:)
diqmtqspsslsaslggrvtitckasqdinkylawyqhkpgkgprllihytstlqpgips
rfsgsgsgrdysfsisnlepedvatyyclqydsllsfgagtklelkradaaptvsifpps
seqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstltl
tkdeyerhnsytceathktstspivksfnrn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6z7yD (D:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlyt
lsssvtvpsstwpsetvtcnvahpasstkvdkkivprdcg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7yD (D:)
evqlvesggglvkpggslklsctasgfafsdydmswvrqtpekrlewvafisnggystyy
pdtvkgrftisrdnaentlylqmsslksedtaiyycarqglryfdywglgttltvssakt
tppsvyplapsmvtlgclvkgyfpepvtvtwnsgslssgvhtfpavlqsdlytlsssvtv
psstwpsetvtcnvahpasstkvdkkivp

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.