PDB entry 6z7v

View 6z7v on RCSB PDB site
Description: Crystal structure of Mindy2 (C266A) in complex with Lys48 linked di-ubiquitin (K48-Ub2)
Class: hydrolase
Keywords: hydrolase, cysteine protease, isopeptidase and ubiquitin binding
Deposited on 2020-06-01, released 2021-06-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase MINDY-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MINDY2, FAM63B, KIAA1164
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NBR6 (9-End)
      • expression tag (8)
      • engineered mutation (34)
  • Chain 'B':
    Compound: Ubiquitin carboxyl-terminal hydrolase MINDY-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MINDY2, FAM63B, KIAA1164
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8NBR6 (9-End)
      • engineered mutation (34)
  • Chain 'C':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vc_
  • Chain 'D':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vd_
  • Chain 'E':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7ve_
  • Chain 'F':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vf_
  • Chain 'G':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vg_
  • Chain 'H':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vh_
  • Chain 'I':
    Compound: Polyubiquitin-C
    Species: Homo sapiens [TaxId:9606]
    Gene: UBC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6z7vi_
  • Heterogens: K, PG4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6z7vC (C:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6z7vD (D:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6z7vE (E:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7vE (E:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6z7vF (F:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7vF (F:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrl

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6z7vG (G:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7vG (G:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrl

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6z7vH (H:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7vH (H:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlr

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6z7vI (I:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlrgg

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7vI (I:)
mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
iqkestlhlvlrlr