PDB entry 6z7h

View 6z7h on RCSB PDB site
Description: Structure of CTX-M-15 E166Q mutant crystallised in the presence of enmetazobactam (AAI101)
Class: antimicrobial protein
Keywords: beta-lactamase, inhibitor, antibiotic resistance, cross-link, ANTIMICROBIAL PROTEIN
Deposited on 2020-05-31, released 2021-06-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-06-09, with a file datestamp of 2021-06-04.
Experiment type: XRAY
Resolution: 1.42 Å
R-factor: N/A
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-lactamase
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1EPV7
      • conflict (46)
      • engineered mutation (142)
    Domains in SCOPe 2.07: d6z7ha_
  • Heterogens: SO4, GOL, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6z7hA (A:)
gpqtadvqqklaelerqsggrlgvalintadnsqilyraderfamcatskvmaaaavlkk
sesepnllnqrveikksdlvnynpiaekhvngtmslaelsaaalqysdnvamnkliahvg
gpasvtafarqlgdetfrldrtqptlntaipgdprdttspramaqtlrnltlgkalgdsq
raqlvtwmkgnttgaasiqaglpaswvvgdktgsggygttndiaviwpkdraplilvtyf
tqpqpkaesrrdvlasaakivtdgl

    Sequence, based on observed residues (ATOM records): (download) 
    >6z7hA (A:)
tadvqqklaelerqsggrlgvalintadnsqilyraderfamcatskvmaaaavlkkses
epnllnqrveikksdlvnynpiaekhvngtmslaelsaaalqysdnvamnkliahvggpa
svtafarqlgdetfrldrtqptlntaipgdprdttspramaqtlrnltlgkalgdsqraq
lvtwmkgnttgaasiqaglpaswvvgdktgsggygttndiaviwpkdraplilvtyftqp
qpkaesrrdvlasaakivtdg