PDB entry 6z6h

View 6z6h on RCSB PDB site
Description: hdac-dc
Deposited on 2020-05-28, released 2021-02-17
The last revision was dated 2021-02-17, with a file datestamp of 2021-02-12.
Experiment type: EM
Resolution: 8.55 Å
R-factor: N/A
AEROSPACI score: -0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase HDA1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA1, YNL021W, N2819
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone deacetylase HDA1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA1, YNL021W, N2819
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: HDA1 complex subunit 2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA2, PLO2, YDR295C
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: HDA1 complex subunit 3,HDA1 complex subunit 3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA3, PLO1, YPR179C
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Histone deacetylase HDA1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA1, YNL021W, N2819
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Histone deacetylase HDA1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA1, YNL021W, N2819
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: HDA1 complex subunit 2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA2, PLO2, YDR295C
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: HDA1 complex subunit 3,HDA1 complex subunit 3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Gene: HDA3, PLO1, YPR179C
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6z6hA (A:)
rqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedprriyriykilae
nglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestekmsreellkete
kgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhaepqaaggfclfs
nvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslhrfemgkyypgt
iqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkpdlviissgfda
adgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsalsvakvligepp
delpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepindsiisknfplqk
airqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhdtsdiwakrnvi
sgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmitsqevliylwdn
yikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlkplvplvdetls
ewyfknslifsnnshqcwkenesrkprkkfgrvlrcdtdglnniieerfeeatdfildsf
e

    Sequence, based on observed residues (ATOM records):
    >6z6hA (A:)
rqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedprriyriykilae
nglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestekmsreellkete
kgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhaepqaaggfclfs
nvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslhrfemgkyypgt
iqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkpdlviissgfda
adgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsalsvakvligepp
delpdplsdpkpeviemidkvirlqskywncfrrrhansgpindsiisknfplqkairqq
qqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhdtsdiwakrnvisgtid
lsssviidnsldfikwgldrkygiidvnipltlfepdnysgmitsqevliylwdnyikyf
psvakiafigigdsysgivhllghrdtravtktvinflgdkqlkplvplvdetlsewyfk
nslifsnnshqcwkkprkkfgrvlrcdtdglnniieerfeeatdfildsfe

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6z6hB (B:)
enslsttskskrqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedpr
riyriykilaenglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestek
msreellketekgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhae
pqaaggfclfsnvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslh
rfemgkyypgtiqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkp
dlviissgfdaadgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsal
svakvligeppdelpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepind
siisknfplqkairqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhd
tsdiwakrnvisgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmit
sqevliylwdnyikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlk
plvplvdetlsewyfknslifsnnshqcwkenesrkprkkfgrvlrcdtdglnniieerf
eeatdfildsfe

    Sequence, based on observed residues (ATOM records):
    >6z6hB (B:)
enslsttskskrqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedpr
riyriykilaenglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestek
msreellketekgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhae
pqaaggfclfsnvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslh
rfemgkyypgtiqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkp
dlviissgfdaadgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsal
svakvligeppdelpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepind
siisknfplqkairqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhd
tsdiwakrnvisgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmit
sqevliylwdnyikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlk
plvplvdetlsewyfknslifsnnshqckkfgrvlrcdtdlnniieerfeeatdfildsf
e

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6z6hC (C:)
kvyylpvtltqfqkdlseilislhaksfkasiigepqadavnkpsglpagpethpyptls
qrqltyifdsniraianhpsllvdhymprqllrmeptessiagshkfqvlnqlinsicfr
dregspnevikcaiiahsikeldlleglilgkkfrtkrlsgtslynekhkfpnlptvdst
inkdgtpnsvsstssnsnstsytgyskddydysvkrnlkkrkintddwlflattkhlkhd
qyllanydidmiisfdpmlevelpalqvlrnnankdipiikllvqnspdhylldseikns
svksshlsnnghvddsqeyeeikssllyflqarnapvnnceidyiklvkcclegkdcnni
lpvldlitldeaskdssdsgfwqpqltklqysstelplwdgpldiktyqtelmhravirl
rdiqdeyakgtvplyekrlnetqrqnqldeiknsvgltfkkkqeveksindsekrlkham
testklqnkinhllknrqelenfnklpsntissenhleegsaladklkeyidknatlfnk
lkelqqanaeksklndelrskyqiesskaaesaqtlkilqesmkslenevngpltkfste
slkkelerlqndfqslkarnkflknyitl

    Sequence, based on observed residues (ATOM records):
    >6z6hC (C:)
kvyylpvtltqfqkdlseilislhaksfkasiiptlsqrqltyifdsniraianhpsllv
dhymprqllrmeptessiagshkfqvlnqlinsicfrdrpnevikcaiiahsikeldlle
glilgkkfrtkrlsgtslynekhkfpnytgyskddydysvkrnlkkrkintddwlflatt
khlkhdqyllanydidmiisfdpmlevelpalqvlrnnankdipiikllvqnspdhylld
seiknsqeyeeikssllyflqarnapvnnceidyiklvkcclegkdcnnilpvldlitsg
fwqpqltklqysstelplwdgpldiktyqtelmhravirlrdiqdeyakgtvplyekrln
etqrqnqldeiknsvgltfkkkqeveksindsekrlkhamtestklqnkinhllknrqel
enfnklpsntissenhleegsaladklkeyidknatlfnklkelqqanaeksklndelrs
kyqiesskaaesaqtlkilqesmkslenevngpltkfstesqndfqslkarnkflknyit
l

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6z6hD (D:)
sgdywlpttmslyqkeltdqivslhysdilryfetshykedvilesmktmclngslvath
pyllidhympkslitrdvpahlaensgkfsvlrdlinlvqeyetetaivcrpgrtmdlle
alllgnkvhikrydghsikskqkandfsctvhlfsseginftkypikskarfdmlicldt
tvdtsqkdiqyllqykrerkgleryapivrlvainsidhcrlffgkkfdknsreylenvt
aamvilrdrlgtlppdlrpiysqklhylvewlenptvpwplpdiyplkqytsmdversll
tevhfkknssnvnyhlssgiithkliqsmgevymdicvqkqelddysclddlqndhlkff
snedekiikeyetvlrtnnenlnrshelevennlkfsqietlekdietlkgslmaqgetl
sklkdafvktdnvqdeiekeervsvsrdtekkymeqeikravdaireneeethklnekqn
gleselklkfekseistkelnekigflkkelklendlneelvgqlsktmdnlenltiprv
rtq

    Sequence, based on observed residues (ATOM records):
    >6z6hD (D:)
sgdywlpttmslyqkeltdqivslhysdilryfetshykedvilesmktmclngslvath
pyllidhympkslitrdvpahlaensgkfsvlrdlinlvqeyetetaivcrpgrtmdlle
alllgnkvhikrydghsikskndfsctvhlfsseginftkypikskarfdmlicldttvd
tsqkdiqyllqykrryapivrlvainsidhcrlffgkkfdknsreylenvtaamvilrdr
lgtlppdlrpiysqklhylvewlenptvpwplpdiyplkqytsmdverslltevhfkkns
snvnyhlssgiithkliqsmgevymdicvqkqelddysclddlqndhlkffsnedekiik
eyetvlrtnnenlnrshelevennlkfsqietlekdietlkgslmaqgetlsklkdafvk
tdnvqdeiekeervsvsrdtekkymeqeikravdaireneeethklnekqngleselklk
fekseistkelnekigflkkelklendlneelvgqlsktmdnlenltiprvrtq

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6z6hF (F:)
rqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedprriyriykilae
nglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestekmsreellkete
kgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhaepqaaggfclfs
nvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslhrfemgkyypgt
iqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkpdlviissgfda
adgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsalsvakvligepp
delpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepindsiisknfplqk
airqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhdtsdiwakrnvi
sgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmitsqevliylwdn
yikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlkplvplvdetls
ewyfknslifsnnshqcwkenesrkprkkfgrvlrcdtdglnniieerfeeatdfildsf
e

    Sequence, based on observed residues (ATOM records):
    >6z6hF (F:)
rqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedprriyriykilae
nglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestekmsreellkete
kgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhaepqaaggfclfs
nvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslhrfemgkyypgt
iqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkpdlviissgfda
adgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsalsvakvligepp
delpdplsdpkpeviemidkvirlqskywncfrrrhansgpindsiisknfplqkairqq
qqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhdtsdiwakrnvisgtid
lsssviidnsldfikwgldrkygiidvnipltlfepdnysgmitsqevliylwdnyikyf
psvakiafigigdsysgivhllghrdtravtktvinflgdkqlkplvplvdetlsewyfk
nslifsnnshqcwkkprkkfgrvlrcdtdglnniieerfeeatdfildsfe

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6z6hG (G:)
enslsttskskrqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedpr
riyriykilaenglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestek
msreellketekgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhae
pqaaggfclfsnvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslh
rfemgkyypgtiqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkp
dlviissgfdaadgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsal
svakvligeppdelpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepind
siisknfplqkairqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhd
tsdiwakrnvisgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmit
sqevliylwdnyikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlk
plvplvdetlsewyfknslifsnnshqcwkenesrkprkkfgrvlrcdtdglnniieerf
eeatdfildsfe

    Sequence, based on observed residues (ATOM records):
    >6z6hG (G:)
enslsttskskrqvivpvcmpkihysplktglcydvrmryhakiftsyfeyidphpedpr
riyriykilaenglindptlsgvddlgdlmlkipvraatseeilevhtkehlefiestek
msreellketekgdsvyfnndsyasarlpcggaieackavvegrvknslavvrppghhae
pqaaggfclfsnvavaaknilknypesvrrimildwdihhgngtqksfyqddqvlyvslh
rfemgkyypgtiqgqydqtgegkgegfncnitwpvggvgdaeymwafeqvvmpmgrefkp
dlviissgfdaadgdtigqchvtpscyghmthmlkslargnlcvvleggynldaiarsal
svakvligeppdelpdplsdpkpeviemidkvirlqskywncfrrrhansgcnfnepind
siisknfplqkairqqqqhylsdefnfvtlplvsmdlpdntvlctpnisesntiiivvhd
tsdiwakrnvisgtidlsssviidnsldfikwgldrkygiidvnipltlfepdnysgmit
sqevliylwdnyikyfpsvakiafigigdsysgivhllghrdtravtktvinflgdkqlk
plvplvdetlsewyfknslifsnnshqckkfgrvlrcdtdlnniieerfeeatdfildsf
e

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6z6hI (I:)
kvyylpvtltqfqkdlseilislhaksfkasiigepqadavnkpsglpagpethpyptls
qrqltyifdsniraianhpsllvdhymprqllrmeptessiagshkfqvlnqlinsicfr
dregspnevikcaiiahsikeldlleglilgkkfrtkrlsgtslynekhkfpnlptvdst
inkdgtpnsvsstssnsnstsytgyskddydysvkrnlkkrkintddwlflattkhlkhd
qyllanydidmiisfdpmlevelpalqvlrnnankdipiikllvqnspdhylldseikns
svksshlsnnghvddsqeyeeikssllyflqarnapvnnceidyiklvkcclegkdcnni
lpvldlitldeaskdssdsgfwqpqltklqysstelplwdgpldiktyqtelmhravirl
rdiqdeyakgtvplyekrlnetqrqnqldeiknsvgltfkkkqeveksindsekrlkham
testklqnkinhllknrqelenfnklpsntissenhleegsaladklkeyidknatlfnk
lkelqqanaeksklndelrskyqiesskaaesaqtlkilqesmkslenevngpltkfste
slkkelerlqndfqslkarnkflknyitl

    Sequence, based on observed residues (ATOM records):
    >6z6hI (I:)
kvyylpvtltqfqkdlseilislhaksfkasiiptlsqrqltyifdsniraianhpsllv
dhymprqllrmeptessiagshkfqvlnqlinsicfrdrpnevikcaiiahsikeldlle
glilgkkfrtkrlsgtslynekhkfpnytgyskddydysvkrnlkkrkintddwlflatt
khlkhdqyllanydidmiisfdpmlevelpalqvlrnnankdipiikllvqnspdhylld
seiknsqeyeeikssllyflqarnapvnnceidyiklvkcclegkdcnnilpvldlitsg
fwqpqltklqysstelplwdgpldiktyqtelmhravirlrdiqdeyakgtvplyekrln
etqrqnqldeiknsvgltfkkkqeveksindsekrlkhamtestklqnkinhllknrqel
enfnklpsntissenhleegsaladklkeyidknatlfnklkelqqanaeksklndelrs
kyqiesskaaesaqtlkilqesmkslenevngpltkfstesqndfqslkarnkflknyit
l

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6z6hJ (J:)
sgdywlpttmslyqkeltdqivslhysdilryfetshykedvilesmktmclngslvath
pyllidhympkslitrdvpahlaensgkfsvlrdlinlvqeyetetaivcrpgrtmdlle
alllgnkvhikrydghsikskqkandfsctvhlfsseginftkypikskarfdmlicldt
tvdtsqkdiqyllqykrerkgleryapivrlvainsidhcrlffgkkfdknsreylenvt
aamvilrdrlgtlppdlrpiysqklhylvewlenptvpwplpdiyplkqytsmdversll
tevhfkknssnvnyhlssgiithkliqsmgevymdicvqkqelddysclddlqndhlkff
snedekiikeyetvlrtnnenlnrshelevennlkfsqietlekdietlkgslmaqgetl
sklkdafvktdnvqdeiekeervsvsrdtekkymeqeikravdaireneeethklnekqn
gleselklkfekseistkelnekigflkkelklendlneelvgqlsktmdnlenltiprv
rtq

    Sequence, based on observed residues (ATOM records):
    >6z6hJ (J:)
sgdywlpttmslyqkeltdqivslhysdilryfetshykedvilesmktmclngslvath
pyllidhympkslitrdvpahlaensgkfsvlrdlinlvqeyetetaivcrpgrtmdlle
alllgnkvhikrydghsikskndfsctvhlfsseginftkypikskarfdmlicldttvd
tsqkdiqyllqykrryapivrlvainsidhcrlffgkkfdknsreylenvtaamvilrdr
lgtlppdlrpiysqklhylvewlenptvpwplpdiyplkqytsmdverslltevhfkkns
snvnyhlssgiithkliqsmgevymdicvqkqelddysclddlqndhlkffsnedekiik
eyetvlrtnnenlnrshelevennlkfsqietlekdietlkgslmaqgetlsklkdafvk
tdnvqdeiekeervsvsrdtekkymeqeikravdaireneeethklnekqngleselklk
fekseistkelnekigflkkelklendlneelvgqlsktmdnlenltiprvrtq