PDB entry 6z6a

View 6z6a on RCSB PDB site
Description: Keap1 macrocycle complex
Class: ligase
Keywords: macrocycle, complex, LIGASE
Deposited on 2020-05-28, released 2020-12-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-12-30, with a file datestamp of 2020-12-25.
Experiment type: XRAY
Resolution: 2.37 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145 (Start-294)
      • conflict (225)
      • conflict (227)
    Domains in SCOPe 2.07: d6z6aa_
  • Chain 'B':
    Compound: Kelch-like ECH-associated protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: KEAP1, INRF2, KIAA0132, KLHL19
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q14145 (Start-294)
      • conflict (225)
      • conflict (227)
    Domains in SCOPe 2.07: d6z6ab_
  • Heterogens: Q9E, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6z6aA (A:)
prgsagapkvgrliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggll
yavggrnnspdgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgc
ihhnsveryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyyper
newrmitamntirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrr
salgitvhqgriyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

    Sequence, based on observed residues (ATOM records): (download) 
    >6z6aA (A:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6z6aB (B:)
prgsagapkvgrliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggll
yavggrnnspdgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgc
ihhnsveryeperdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyyper
newrmitamntirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrr
salgitvhqgriyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt

    Sequence, based on observed residues (ATOM records): (download) 
    >6z6aB (B:)
grliytaggyfrqslsyleaynpsdgtwlrladlqvprsglagcvvggllyavggrnnsp
dgntdssaldcynpmtnqwspcapmsvprnrigvgvidghiyavggshgcihhnsverye
perdewhlvapmltrrigvgvavlnrllyavggfdgtnrlnsaecyypernewrmitamn
tirsgagvcvlhnciyaaggydgqdqlnsverydvatatwtfvapmkhrrsalgitvhqg
riyvlggydghtfldsvecydpdtdtwsevtrmtsgrsgvgvavt