PDB entry 6yzp

View 6yzp on RCSB PDB site
Description: Carborane nido-hexyl-sulfonamide in complex with CA IX mimic
Class: lyase
Keywords: carbonic anhydrase, ca inhibitor, lyase
Deposited on 2020-05-07, released 2020-10-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 1.35 Å
R-factor: N/A
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (Start-259)
      • engineered mutation (64)
      • engineered mutation (66)
      • engineered mutation (68)
      • engineered mutation (90)
      • engineered mutation (129)
      • engineered mutation (168)
      • engineered mutation (202)
    Domains in SCOPe 2.08: d6yzpa_
  • Heterogens: Q3H, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yzpA (A:)
mshhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhl
vhwntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdp
rgllpesldywtypgslttpplaecvtwivlkepisvsseqvlkfrklnfngegepeelm
vdnwrpaqplknrqikasfk

    Sequence, based on observed residues (ATOM records): (download) 
    >6yzpA (A:)
hhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnn
ghsfqvtfddsqdkavlkggpldgtyrllqfhfhwgsldgqgsehtvdkkkyaaelhlvh
wntkygdvgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktegksadftnfdprg
llpesldywtypgslttpplaecvtwivlkepisvsseqvlkfrklnfngegepeelmvd
nwrpaqplknrqikasfk