PDB entry 6yyz

View 6yyz on RCSB PDB site
Description: tRNA-Guanine Transglycosylase (TGT) labeled with 5-fluorotryptophan in co-crystallized complex with 6-amino-2-(methylamino)-4-(2-((2R,3R,4R,5R)-3,4,5-trimethoxytetrahydrofuran-2-yl)ethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Class: transferase
Keywords: transferase, tgt, tRNA-guanine transglycosylase, guanine insertion enzyme, homodimer
Deposited on 2020-05-06, released 2020-05-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-13, with a file datestamp of 2020-05-08.
Experiment type: XRAY
Resolution: 1.21 Å
R-factor: N/A
AEROSPACI score: 0.64 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • engineered mutation (313)
    Domains in SCOPe 2.08: d6yyza_
  • Heterogens: 725, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yyzA (A:)
gsmveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpet
vratgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqs
eegvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrw
akrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqd
emfrvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdg
pinirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlm
qkirdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >6yyzA (A:)
drprfsfsiaaregkartgtiemkrgvirtpafmpvgtagadiilgntyhlmlrpgaeri
aklgglhsfmgwdrpiltdsggyqvmslssltkqseegvtfkshldgsrhmlspersiei
qhllgsdivmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaalfgiqq
gsvfenlrqqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphylmgvg
kpddivgavergidmfdcvlptrsgrngqaftwdgpinirnarfsedlkpldsechcavc
qkwsrayihhlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryfa