PDB entry 6ywm

View 6ywm on RCSB PDB site
Description: Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES
Class: viral protein
Keywords: NSP3, macrodomain, ADP-ribose-1"-phosphatase, ADRP, Covid-19, SARS-COV-2, Structural Genomics, Structural Genomics Consortium, SGC, VIRAL PROTEIN
Deposited on 2020-04-29, released 2020-05-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-07-07, with a file datestamp of 2021-07-02.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NSP3 macrodomain
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-172)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d6ywma1, d6ywma2
  • Chain 'B':
    Compound: NSP3 macrodomain
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-172)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d6ywmb1, d6ywmb2
  • Chain 'C':
    Compound: NSP3 macrodomain
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: rep, 1a-1b
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTD1 (3-172)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d6ywmc1, d6ywmc2
  • Heterogens: MES, EDO, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ywmA (A:)
ghmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnn
amqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqh
evllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssflemk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ywmA (A:)
hmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnna
mqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqhe
vllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssflemk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ywmB (B:)
ghmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnn
amqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqh
evllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssflemk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ywmB (B:)
ghmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnn
amqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqh
evllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssfle

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ywmC (C:)
ghmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnn
amqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqh
evllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssflemk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ywmC (C:)
hmvnsfsgylkltdnvyiknadiveeakkvkptvvvnaanvylkhgggvagalnkatnna
mqvesddyiatngplkvggscvlsghnlakhclhvvgpnvnkgediqllksayenfnqhe
vllapllsagifgadpihslrvcvdtvrtnvylavfdknlydklvssfl