PDB entry 6yvh

View 6yvh on RCSB PDB site
Description: CWC22-CWC27-EIF4A3 Complex
Class: RNA binding protein
Keywords: EJC Helicase, RNA BINDING PROTEIN
Deposited on 2020-04-28, released 2020-05-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-05-13, with a file datestamp of 2020-05-08.
Experiment type: XRAY
Resolution: 3.19 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: pre-mRNA-splicing factor cwc22 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC22, KIAA1604, NCM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HCG8 (Start-290)
• Chain 'B':
  Compound: pre-mRNA-splicing factor cwc22 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC22, KIAA1604, NCM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HCG8 (Start-290)
• Chain 'C':
  Compound: Spliceosome-associated protein CWC27 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC27, SDCCAG10, UNQ438/PRO871
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6UX04 (3-End)
• Chain 'D':
  Compound: pre-mRNA-splicing factor cwc22 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC22, KIAA1604, NCM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HCG8 (Start-290)
• Chain 'E':
  Compound: Spliceosome-associated protein CWC27 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC27, SDCCAG10, UNQ438/PRO871
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6UX04 (3-End)
• Chain 'F':
  Compound: pre-mRNA-splicing factor cwc22 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC22, KIAA1604, NCM
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9HCG8 (Start-290)
• Chain 'G':
  Compound: Spliceosome-associated protein CWC27 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC27, SDCCAG10, UNQ438/PRO871
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6UX04 (3-End)
• Chain 'H':
  Compound: Eukaryotic initiation factor 4A-III
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF4A3, DDX48, KIAA0111
  Database cross-references and differences (RAF-indexed):
  • Uniprot P38919 (0-165)
  Domains in SCOPe 2.07: d6yvhh_
• Chain 'I':
  Compound: Spliceosome-associated protein CWC27 homolog
  Species: Homo sapiens [TaxId:9606]
  Gene: CWC27, SDCCAG10, UNQ438/PRO871
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q6UX04 (3-End)
• Chain 'J':
  Compound: Eukaryotic initiation factor 4A-III
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF4A3, DDX48, KIAA0111
  Database cross-references and differences (RAF-indexed):
  • Uniprot P38919 (0-165)
  Domains in SCOPe 2.07: d6yvhj_
• Chain 'K':
  Compound: Eukaryotic initiation factor 4A-III
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF4A3, DDX48, KIAA0111
  Database cross-references and differences (RAF-indexed):
  • Uniprot P38919 (0-165)
  Domains in SCOPe 2.07: d6yvhk_
• Chain 'L':
  Compound: Eukaryotic initiation factor 4A-III
  Species: Homo sapiens [TaxId:9606]
  Gene: EIF4A3, DDX48, KIAA0111
  Database cross-references and differences (RAF-indexed):
  • Uniprot P38919 (0-165)
  Domains in SCOPe 2.07: d6yvhl_

PDB Chain Sequences:

• Chain 'A':
  No sequence available.
  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  No sequence available.
  
  
• Chain 'D':
  No sequence available.
  
  
• Chain 'E':
  No sequence available.
  
  
• Chain 'F':
  No sequence available.
  
  
• Chain 'G':
  No sequence available.
  
  
• Chain 'H':
  Sequence, based on SEQRES records: (download)
  

  >6yvhH (H:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrelyihri
  grsgrygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6yvhH (H:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwgldvpqvsliinydlpnnrelyihrigr
  sgrrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  
• Chain 'I':
  No sequence available.
  
  
• Chain 'J':
  Sequence, based on SEQRES records: (download)
  

  >6yvhJ (J:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrelyihri
  grsgrygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6yvhJ (J:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwdvpqvsliinydlpnnrelyihrigrsg
  rygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  
• Chain 'K':
  Sequence, based on SEQRES records: (download)
  

  >6yvhK (K:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrelyihri
  grsgrygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6yvhK (K:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwgldvpqvsliinydlpnnrelyihrigr
  sgrygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  
• Chain 'L':
  Sequence, based on SEQRES records: (download)
  

  >6yvhL (L:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwargldvpqvsliinydlpnnrelyihri
  grsgrygrkgvainfvknddirilrdieqyystqidempmnvadli
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6yvhL (L:)
  ltlegikqffvavereewkfdtlcdlydtltitqavifcntkrkvdwltekmreanftvs
  smhgdmpqkeresimkefrsgasrvlistdvwdvpqvsliinydlpnnrelyihrigrsg
  rygrkgvainfvknddirilrdieqyystqidempmnvadli