PDB entry 6yte

View 6yte on RCSB PDB site
Description: CLK1 bound with benzothiazole Tg003 (Cpd 2)
Class: transferase
Keywords: Inhibitor, Complex, CLK1, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2020-04-24, released 2020-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-14, with a file datestamp of 2020-10-09.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: Dual specificity protein kinase CLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK1, CLK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49759 (2-338)
      • expression tag (1)
      • conflict (286)
    Domains in SCOPe 2.08: d6ytec1, d6ytec2
  • Heterogens: EAE, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6yteC (C:)
    smhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaars
    eiqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhi
    rkmayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvd
    fgsatyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdsk
    ehlammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdv
    eherlfdliqkmleydpakritlrealkhpffdllkksi
    

    Sequence, based on observed residues (ATOM records): (download)
    >6yteC (C:)
    mhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaarse
    iqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhir
    kmayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvdf
    gsatyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdske
    hlammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdve
    herlfdliqkmleydpakritlrealkhpffdllkksi