PDB entry 6ysn

View 6ysn on RCSB PDB site
Description: human trpc5 in complex with pico145 (hc-608)
Deposited on 2020-04-22, released 2020-12-02
The last revision was dated 2020-12-09, with a file datestamp of 2020-12-04.
Experiment type: EM
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5
    Species: Homo sapiens [TaxId:9606]
    Gene: TRPC5, TRP5
    Database cross-references and differences (RAF-indexed):
  • Heterogens: PJQ

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ysnA (A:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasglevrqt
vdealkdaqtssglgvlfqgpmaqlyykkvnyspyrdriplqivraetelsaeekaflna
vekgdyatvkqalqeaeiyynvnincmdplgrsalliaienenleimelllnhsvyvgda
llyairkevvgavelllsyrrpsgekqvptlmmdtqfseftpditpimlaahtnnyeiik
llvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslialssedpilt
afrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhrddhseel
dpqkyhdlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigf
lfpmlsiaylisprsnlglfikkpfikfichtasyltflfmlllasqhivrtdlhvqgpp
ptvvewmilpwvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkimayvk
yngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilk
flfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsv
fgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiew
kfartklwmsyfdeggtlpppfniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsf
ternadsliqnqhyqevirnlvkryvaamirnsktheglteenfkelkqdissfryevld
llgnrk

    Sequence, based on observed residues (ATOM records):
    >6ysnA (A:)
riplqivraetelsaeekafvnincmdplgrsalliaienenlyvgdallyairkevvga
velllsqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncvecvsssevd
slrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkaeyeelsqqc
klfakdlldqarssreleiilnhrdlaklkvaikyhqkefvaqpncqqllatlwydgfpg
wrrkhwvvklltcmtigflfpmlsiaylisprsnlglfikkpfikfichtasyltflfml
llasqdlhvqgppptvvewmilpwvlgfiwgeikemwdggyihdwwnlmdfamnslylat
islkimayvkyngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqis
lgrmlldilkflfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlf
etlqslfwsvfgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyq
liadhadiewkfartklwmsyfdeggtlpppfniinadsliqnqhyqevirnlvkryvaa
mirnsk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ysnB (B:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasglevrqt
vdealkdaqtssglgvlfqgpmaqlyykkvnyspyrdriplqivraetelsaeekaflna
vekgdyatvkqalqeaeiyynvnincmdplgrsalliaienenleimelllnhsvyvgda
llyairkevvgavelllsyrrpsgekqvptlmmdtqfseftpditpimlaahtnnyeiik
llvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslialssedpilt
afrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhrddhseel
dpqkyhdlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigf
lfpmlsiaylisprsnlglfikkpfikfichtasyltflfmlllasqhivrtdlhvqgpp
ptvvewmilpwvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkimayvk
yngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilk
flfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsv
fgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiew
kfartklwmsyfdeggtlpppfniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsf
ternadsliqnqhyqevirnlvkryvaamirnsktheglteenfkelkqdissfryevld
llgnrk

    Sequence, based on observed residues (ATOM records):
    >6ysnB (B:)
riplqivraetelsaeekafvnincmdplgrsalliaienenlyvgdallyairkevvga
velllsqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncvecvsssevd
slrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkaeyeelsqqc
klfakdlldqarssreleiilnhrdlaklkvaikyhqkefvaqpncqqllatlwydgfpg
wrrkhwvvklltcmtigflfpmlsiaylisprsnlglfikkpfikfichtasyltflfml
llasqdlhvqgppptvvewmilpwvlgfiwgeikemwdggyihdwwnlmdfamnslylat
islkimayvkyngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqis
lgrmlldilkflfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlf
etlqslfwsvfgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyq
liadhadiewkfartklwmsyfdeggtlpppfniinadsliqnqhyqevirnlvkryvaa
mirnsk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ysnC (C:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasglevrqt
vdealkdaqtssglgvlfqgpmaqlyykkvnyspyrdriplqivraetelsaeekaflna
vekgdyatvkqalqeaeiyynvnincmdplgrsalliaienenleimelllnhsvyvgda
llyairkevvgavelllsyrrpsgekqvptlmmdtqfseftpditpimlaahtnnyeiik
llvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslialssedpilt
afrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhrddhseel
dpqkyhdlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigf
lfpmlsiaylisprsnlglfikkpfikfichtasyltflfmlllasqhivrtdlhvqgpp
ptvvewmilpwvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkimayvk
yngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilk
flfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsv
fgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiew
kfartklwmsyfdeggtlpppfniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsf
ternadsliqnqhyqevirnlvkryvaamirnsktheglteenfkelkqdissfryevld
llgnrk

    Sequence, based on observed residues (ATOM records):
    >6ysnC (C:)
riplqivraetelsaeekafvnincmdplgrsalliaienenlyvgdallyairkevvga
velllsqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncvecvsssevd
slrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkaeyeelsqqc
klfakdlldqarssreleiilnhrdlaklkvaikyhqkefvaqpncqqllatlwydgfpg
wrrkhwvvklltcmtigflfpmlsiaylisprsnlglfikkpfikfichtasyltflfml
llasqdlhvqgppptvvewmilpwvlgfiwgeikemwdggyihdwwnlmdfamnslylat
islkimayvkyngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqis
lgrmlldilkflfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlf
etlqslfwsvfgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyq
liadhadiewkfartklwmsyfdeggtlpppfniinadsliqnqhyqevirnlvkryvaa
mirnsk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ysnD (D:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasglevrqt
vdealkdaqtssglgvlfqgpmaqlyykkvnyspyrdriplqivraetelsaeekaflna
vekgdyatvkqalqeaeiyynvnincmdplgrsalliaienenleimelllnhsvyvgda
llyairkevvgavelllsyrrpsgekqvptlmmdtqfseftpditpimlaahtnnyeiik
llvqkrvtiprphqircncvecvsssevdslrhsrsrlniykalaspslialssedpilt
afrlgwelkelskvenefkaeyeelsqqcklfakdlldqarssreleiilnhrddhseel
dpqkyhdlaklkvaikyhqkefvaqpncqqllatlwydgfpgwrrkhwvvklltcmtigf
lfpmlsiaylisprsnlglfikkpfikfichtasyltflfmlllasqhivrtdlhvqgpp
ptvvewmilpwvlgfiwgeikemwdggfteyihdwwnlmdfamnslylatislkimayvk
yngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqislgrmlldilk
flfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlfetlqslfwsv
fgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyqliadhadiew
kfartklwmsyfdeggtlpppfniipspksflylgnwfnntfcpkrdpdgrrrrrnlrsf
ternadsliqnqhyqevirnlvkryvaamirnsktheglteenfkelkqdissfryevld
llgnrk

    Sequence, based on observed residues (ATOM records):
    >6ysnD (D:)
riplqivraetelsaeekafvnincmdplgrsalliaienenlyvgdallyairkevvga
velllsqfseftpditpimlaahtnnyeiikllvqkrvtiprphqircncvecvsssevd
slrhsrsrlniykalaspslialssedpiltafrlgwelkelskvenefkaeyeelsqqc
klfakdlldqarssreleiilnhrdlaklkvaikyhqkefvaqpncqqllatlwydgfpg
wrrkhwvvklltcmtigflfpmlsiaylisprsnlglfikkpfikfichtasyltflfml
llasqdlhvqgppptvvewmilpwvlgfiwgeikemwdggyihdwwnlmdfamnslylat
islkimayvkyngsrpreewemwhptliaealfaisnilsslrlislftanshlgplqis
lgrmlldilkflfiyclvllafanglnqlyfyyetraidepnnckgircekqnnafstlf
etlqslfwsvfgllnlyvtnvkarheftefvgatmfgtynvislvvllnmliammnnsyq
liadhadiewkfartklwmsyfdeggtlpppfniinadsliqnqhyqevirnlvkryvaa
mirnsk