PDB entry 6yrm

View 6yrm on RCSB PDB site
Description: Transaldolase variant T30A from T. acidophilum in complex with D-fructose 6-phosphate Schiff-base intermediate
Class: transferase
Keywords: ALPHA-BETA BARREL, CONFORMATIONAL SELECTION, DOMAIN SWAPPING, TRANSFERASE, TIM BARREL, SCHIFF BASE, Large-scale motions, Substrate binding, rate-determining product release
Deposited on 2020-04-20, released 2021-05-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-12, with a file datestamp of 2021-05-07.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Probable transaldolase
    Species: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [TaxId:273075]
    Gene: tal, Ta0616
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HKI3 (0-222)
      • engineered mutation (29)
      • variant (125)
    Domains in SCOPe 2.08: d6yrma_
  • Chain 'B':
    Compound: Probable transaldolase
    Species: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [TaxId:273075]
    Gene: tal, Ta0616
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HKI3 (0-222)
      • engineered mutation (29)
      • variant (125)
    Domains in SCOPe 2.08: d6yrmb_
  • Chain 'C':
    Compound: Probable transaldolase
    Species: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [TaxId:273075]
    Gene: tal, Ta0616
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HKI3 (0-222)
      • engineered mutation (29)
      • variant (125)
    Domains in SCOPe 2.08: d6yrmc_
  • Chain 'D':
    Compound: Probable transaldolase
    Species: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [TaxId:273075]
    Gene: tal, Ta0616
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HKI3 (0-222)
      • engineered mutation (29)
      • variant (125)
    Domains in SCOPe 2.08: d6yrmd_
  • Chain 'E':
    Compound: Probable transaldolase
    Species: Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) [TaxId:273075]
    Gene: tal, Ta0616
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HKI3 (0-222)
      • engineered mutation (29)
      • variant (125)
    Domains in SCOPe 2.08: d6yrme_
  • Heterogens: F6R, GOL, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yrmA (A:)
mkifldtanideirtgvnwgivdgvttnpaliskeavngkkygdiireilkivdgpvsve
vvstkyegmveearkihglgdnavvkipmtedglraiktlssehintnctlvfnpiqall
aakagvtyvspfvgrlddigedgmqiidmirtifnnyiiktqilvasirnpihvlrsavi
gadvvtvpfnvlkslmkhpktdeglakfledwkkvspdgklil

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yrmB (B:)
mkifldtanideirtgvnwgivdgvttnpaliskeavngkkygdiireilkivdgpvsve
vvstkyegmveearkihglgdnavvkipmtedglraiktlssehintnctlvfnpiqall
aakagvtyvspfvgrlddigedgmqiidmirtifnnyiiktqilvasirnpihvlrsavi
gadvvtvpfnvlkslmkhpktdeglakfledwkkvspdgklil

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yrmC (C:)
mkifldtanideirtgvnwgivdgvttnpaliskeavngkkygdiireilkivdgpvsve
vvstkyegmveearkihglgdnavvkipmtedglraiktlssehintnctlvfnpiqall
aakagvtyvspfvgrlddigedgmqiidmirtifnnyiiktqilvasirnpihvlrsavi
gadvvtvpfnvlkslmkhpktdeglakfledwkkvspdgklil

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yrmD (D:)
mkifldtanideirtgvnwgivdgvttnpaliskeavngkkygdiireilkivdgpvsve
vvstkyegmveearkihglgdnavvkipmtedglraiktlssehintnctlvfnpiqall
aakagvtyvspfvgrlddigedgmqiidmirtifnnyiiktqilvasirnpihvlrsavi
gadvvtvpfnvlkslmkhpktdeglakfledwkkvspdgklil

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yrmE (E:)
mkifldtanideirtgvnwgivdgvttnpaliskeavngkkygdiireilkivdgpvsve
vvstkyegmveearkihglgdnavvkipmtedglraiktlssehintnctlvfnpiqall
aakagvtyvspfvgrlddigedgmqiidmirtifnnyiiktqilvasirnpihvlrsavi
gadvvtvpfnvlkslmkhpktdeglakfledwkkvspdgklil