PDB entry 6ynt

View 6ynt on RCSB PDB site
Description: crystal structure of the camp-dependent protein kinase a in complex with aminofasudil and pki (5-24)
Deposited on 2020-04-14, released 2020-10-14
The last revision was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 1.52 Å
R-factor: N/A
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Cricetulus griseus [TaxId:10029]
    Gene: PRKACA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: cAMP-dependent protein kinase inhibitor alpha
    Species: Mus musculus, synthetic [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: LRT, MPD, DMS, MRD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6yntA (A:)
ghmgnaaaakkgseqesvkeflakakeeflkkwespsqntaqldhfdriktlgtgsfgrv
mlvkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnly
mvmeyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqq
gyiqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagypp
ffadqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwf
attdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

    Sequence, based on observed residues (ATOM records):
    >6yntA (A:)
aakkgseqesvkeflakakeeflkkwespsqntaqldhfdriktlgtgsfgrvmlvkhke
tgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvp
ggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtd
fgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpi
qiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwia
iyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6yntB (B:)
ttyadfiasgrtgrrnaihd

    Sequence, based on observed residues (ATOM records):
    >6yntB (B:)
ttyadfiasgrtgrrnaih