PDB entry 6yna

View 6yna on RCSB PDB site
Description: crystal structure of camp-dependent protein kinase (pka) in complex with fasudil (m77, soaked)
Deposited on 2020-04-13, released 2020-10-14
The last revision was dated 2021-01-20, with a file datestamp of 2021-01-15.
Experiment type: XRAY
Resolution: 1.47 Å
R-factor: N/A
AEROSPACI score: 0.58 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Cricetulus griseus [TaxId:10029]
    Gene: PRKACA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25321 (2-352)
      • expression tag (0-1)
  • Chain 'B':
    Compound: cAMP-dependent protein kinase inhibitor alpha
    Species: Mus musculus, synthetic [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63248
      • engineered mutation (2)
      • engineered mutation (9)
  • Heterogens: M77, MPD, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6ynaA (A:)
ghmgnaaaakkgseqesvkeflakakeeflkkwespsqntaqldhfdriktlgtgsfgrv
mlvkhketgnhyamkildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnly
mvmeyvpggemfshlrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqq
gyiqvtdfgfakrvkgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagypp
ffadqpiqiyekivsgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwf
attdwiaiyqrkveapfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ynaB (B:)
iaagrtgrrqaihdilvaa

    Sequence, based on observed residues (ATOM records):
    >6ynaB (B:)
agrtgrrqaihdi