PDB entry 6yn2

View 6yn2 on RCSB PDB site
Description: Crystal structure of Renilla reniformis luciferase variant RLuc8-W121F/E144Q in complex with a coelenteramide (the postcatalytic enzyme-product complex)
Class: luminescent protein
Keywords: bioluminscence, coelenteramide-bound enzyme, LUMINESCENT PROTEIN
Deposited on 2020-04-10, released 2021-04-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-21, with a file datestamp of 2021-04-16.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Coelenterazine h 2-monooxygenase
    Species: Renilla reniformis [TaxId:6136]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27652 (Start-310)
      • conflict (54)
      • engineered mutation (120)
      • conflict (123)
      • conflict (129)
      • conflict (135)
      • conflict (142)
      • engineered mutation (143)
      • conflict (184)
      • conflict (252)
      • conflict (286)
    Domains in SCOPe 2.08: d6yn2a_
  • Chain 'B':
    Compound: Coelenterazine h 2-monooxygenase
    Species: Renilla reniformis [TaxId:6136]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P27652
      • conflict (54)
      • engineered mutation (120)
      • conflict (123)
      • conflict (129)
      • conflict (135)
      • conflict (142)
      • engineered mutation (143)
      • conflict (184)
      • conflict (252)
      • conflict (286)
    Domains in SCOPe 2.08: d6yn2b_
  • Heterogens: ACT, CEI, GOL, K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yn2A (A:)
mtskvydpeqrkrmitgpqwwarckqmnvldsfinyydsekhaenaviflhgnatssylw
rhvvphiepvarciipdligmgksgksgngsyrlldhykyltawfellnlpkkiifvghd
fgaalafhyayehqdrikaivhmqsvvdvieswdewpdieedialikseegekmvlennf
fvetvlpskimrklepeefaaylepfkekgevrrptlswpreiplvkggkpdvvqivrny
naylrasddlpklfiesdpgffsnaivegakkfpntefvkvkglhflqedapdemgkyik
sfvervlkneqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6yn2A (A:)
tskvydpeqrkrmitgpqwwarckqmnvldsfinyydsekhaenaviflhgnatssylwr
hvvphiepvarciipdligmgksgksgngsyrlldhykyltawfellnlpkkiifvghdf
gaalafhyayehqdrikaivhmqsvvdvieswdewpdieedialikseegekmvlennff
vetvlpskimrklepeefaaylepfkekgevrrptlswpreiplvkggkpdvvqivrnyn
aylrasddlpklfiesdpgffsnaivegakkfpntefvkvkglhflqedapdemgkyiks
fvervlkneq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6yn2B (B:)
mtskvydpeqrkrmitgpqwwarckqmnvldsfinyydsekhaenaviflhgnatssylw
rhvvphiepvarciipdligmgksgksgngsyrlldhykyltawfellnlpkkiifvghd
fgaalafhyayehqdrikaivhmqsvvdvieswdewpdieedialikseegekmvlennf
fvetvlpskimrklepeefaaylepfkekgevrrptlswpreiplvkggkpdvvqivrny
naylrasddlpklfiesdpgffsnaivegakkfpntefvkvkglhflqedapdemgkyik
sfvervlkneqhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6yn2B (B:)
tskvydpeqrkrmitgpqwwarckqmnvldsfinyydsekhaenaviflhgnatssylwr
hvvphiepvarciipdligmgksgksgngsyrlldhykyltawfellnlpkkiifvghdf
gaalafhyayehqdrikaivhmqsvvdvieswdewpdieedialikseegekmvlennff
vetvlpskimrklepeefaaylepfkekgevrrptlswpreiplvkggkpdvvqivrnyn
aylrasddlpklfiesdpgffsnaivegakkfpntefvkvkglhflqedapdemgkyiks
fvervlkne