PDB entry 6yla

View 6yla on RCSB PDB site
Description: Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab
Class: viral protein
Keywords: SARS-CoV-2 Spike protein, RBD, CR3022, complex, VIRAL PROTEIN
Deposited on 2020-04-06, released 2020-04-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ylaa_
  • Chain 'B':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YLA (0-End)
    Domains in SCOPe 2.08: d6ylab_
  • Chain 'C':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YLA (0-End)
    Domains in SCOPe 2.08: d6ylac1, d6ylac2
  • Chain 'E':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DTC2 (3-End)
      • expression tag (0-2)
    Domains in SCOPe 2.08: d6ylae1, d6ylae2
  • Chain 'H':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YLA (0-End)
    Domains in SCOPe 2.08: d6ylah_
  • Chain 'L':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YLA (0-End)
    Domains in SCOPe 2.08: d6ylal1, d6ylal2
  • Heterogens: DMS, MLI, NAG, 1PE, PG0, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ylaA (A:)
etgpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkkstnkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaA (A:)
itnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlc
ftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcgpkkstn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ylaB (B:)
tqmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetr
yspsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaB (B:)
tqmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetr
yspsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvas
tkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysls
svvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ylaC (C:)
diqltqspdslavslgeratinckssqsvlyssinknylawyqqkpgqppklliywastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyystpytfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaC (C:)
diqltqspdslavslgeratinckssqsvlyssinknylawyqqkpgqppklliywastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyystpytfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6ylaE (E:)
etgpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkkstnkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaE (E:)
etgpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptk
lndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvg
gnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyq
pyrvvvlsfellhapatvcgpkk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6ylaH (H:)
tqmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetr
yspsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaH (H:)
tqmqlvqsgtevkkpgeslkisckgsgygfitywigwvrqmpgkglewmgiiypgdsetr
yspsfqgqvtisadksintaylqwsslkasdtaiyycaggsgistpmdvwgqgttvtvas
tkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysls
svvtvpssslgtqtyicnvnhkpsntkvdkkvepks

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6ylaL (L:)
diqltqspdslavslgeratinckssqsvlyssinknylawyqqkpgqppklliywastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyystpytfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6ylaL (L:)
diqltqspdslavslgeratinckssqsvlyssinknylawyqqkpgqppklliywastr
esgvpdrfsgsgsgtdftltisslqaedvavyycqqyystpytfgqgtkveikrtvaaps
vfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstys
lsstltlskadyekhkvyacevthqglsspvtksfnrge