PDB entry 6yk1

View 6yk1 on RCSB PDB site
Description: Crystal structure of mouse pyridoxal kinase in complex with ATP-gamma-S and artesunate
Class: transferase
Keywords: PDXK, PLP, PL, Vitamin B6, Enzyme, artemisinin, artesunate, TRANSFERASE
Deposited on 2020-04-05, released 2021-04-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2021-04-14, with a file datestamp of 2021-04-09.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pyridoxal kinase
    Species: Mus musculus [TaxId:10090]
    Gene: Pdxk, Pkh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6yk1a_
  • Chain 'B':
    Compound: Pyridoxal kinase
    Species: Mus musculus [TaxId:10090]
    Gene: Pdxk, Pkh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6yk1b_
  • Chain 'C':
    Compound: Pyridoxal kinase
    Species: Mus musculus [TaxId:10090]
    Gene: Pdxk, Pkh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6yk1c_
  • Chain 'D':
    Compound: Pyridoxal kinase
    Species: Mus musculus [TaxId:10090]
    Gene: Pdxk, Pkh
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6yk1d_
  • Heterogens: D95, GOL, PG4, AGS, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yk1A (A:)
gpmegecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlk
sqelhelyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgd
kwngegsmyvpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcm
gpdtvvitssdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfa
amllawthkhpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskr
diedpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >6yk1A (A:)
ecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlksqelh
elyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgdkgsmy
vpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcmgpdtvvits
sdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfaamllawthk
hpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskrdiedpeivv
qatvl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6yk1B (B:)
gpmegecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlk
sqelhelyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgd
kwngegsmyvpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcm
gpdtvvitssdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfa
amllawthkhpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskr
diedpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >6yk1B (B:)
ecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlksqelh
elyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgdksmyv
pqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcmgpdtvvitss
dlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfaamllawthkh
pdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskrdiedpeivvq
atvl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6yk1C (C:)
gpmegecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlk
sqelhelyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgd
kwngegsmyvpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcm
gpdtvvitssdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfa
amllawthkhpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskr
diedpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >6yk1C (C:)
ecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlksqelh
elyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgdksmyv
pqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcmgpdtvvitss
dlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfaamllawthkh
pdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskrdiedpeivvq
atvl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6yk1D (D:)
gpmegecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlk
sqelhelyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgd
kwngegsmyvpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcm
gpdtvvitssdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfa
amllawthkhpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskr
diedpeivvqatvl

    Sequence, based on observed residues (ATOM records): (download) 
    >6yk1D (D:)
ecrvlsiqshvvrgyvgnraamfplqvlgfevdavnsvqfsnhtgyahwkgqvlksqelh
elyeglkvndvnkydyvltgytrdksflamvvdivrelkqqnsrlvyvcdpvmgdkgsmy
vpqdllpvyrdkvvpvadiitpnqfeaellsgrkihsqeeafevmdmlhcmgpdtvvits
sdlpssqgsdylialgsqrmrkpdgstvtqrirmemrkveavfvgtgdlfaamllawthk
hpdnlkvacektvsamqhvlqrtircakaeagegqkpspaqlelrmvqskrdiedpeivv
qatvl