PDB entry 6yjy

View 6yjy on RCSB PDB site
Description: Crystal structure of human glutaminyl cyclase in complex with neurotensin 1-5
Class: transferase
Keywords: alpha-beta protein, metalloprotein, transferase, intermediate
Deposited on 2020-04-05, released 2020-07-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-24.
Experiment type: XRAY
Resolution: 1.67 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutaminyl-peptide cyclotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: QPCT
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16769 (2-328)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6yjya1, d6yjya2
  • Chain 'B':
    Compound: Glutaminyl-peptide cyclotransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: QPCT
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16769 (2-328)
      • expression tag (0-1)
    Domains in SCOPe 2.08: d6yjyb1, d6yjyb2
  • Heterogens: ZN, PCA, LEU, TYR, GLN, MES, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yjyA (A:)
gpawpeeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhim
qriqrlqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfshwnnr
vfvgatdsavpcammlelaraldkkllslktvsdskpdlslqliffdgeeaflhwspqds
lygsrhlaakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlq
aiehelhelgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtm
ddneenldestidnlnkilqvfvleylhl

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6yjyB (B:)
gpawpeeknyhqpailnssalrqiaegtsisemwqndlqpllierypgspgsyaarqhim
qriqrlqadwvleidtflsqtpygyrsfsniistlnptakrhlvlachydskyfshwnnr
vfvgatdsavpcammlelaraldkkllslktvsdskpdlslqliffdgeeaflhwspqds
lygsrhlaakmastphppgargtsqlhgmdllvlldligapnptfpnffpnsarwferlq
aiehelhelgllkdhslegryfqnysyggviqddhipflrrgvpvlhlipspfpevwhtm
ddneenldestidnlnkilqvfvleylhl