PDB entry 6ygs

View 6ygs on RCSB PDB site
Description: tRNA-guanine Transglycosylase (TGT) in co-crystallized complex with 6-amino-2-(methylamino)-4-(4-(trifluoromethyl)phenethyl)-3,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
Class: transferase
Keywords: transferase, tgt, tRNA-guanine transglycosylase, guanine insertion enzyme, homodimer
Deposited on 2020-03-27, released 2020-04-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-04-08, with a file datestamp of 2020-04-03.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Queuine tRNA-ribosyltransferase
    Species: Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) [TaxId:264203]
    Gene: tgt, ZMO0363
    Database cross-references and differences (RAF-indexed):
    • Uniprot P28720
      • conflict (313)
    Domains in SCOPe 2.08: d6ygsa_
  • Heterogens: ZN, OQQ, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ygsA (A:)
gsmveataqetdrprfsfsiaaregkartgtiemkrgvirtpafmpvgtaatvkalkpet
vratgadiilgntyhlmlrpgaeriaklgglhsfmgwdrpiltdsggyqvmslssltkqs
eegvtfkshldgsrhmlspersieiqhllgsdivmafdectpypatpsraassmersmrw
akrsrdafdsrkeqaenaalfgiqqgsvfenlrqqsadalaeigfdgyavgglavgegqd
emfrvldfsvpmlpddkphylmgvgkpddivgavergidmfdcvlptrsgrngqaftwdg
pinirnarfsedlkpldsechcavcqkwsrayihhlirageilgamlmtehniafyqqlm
qkirdsisegrfsqfaqdfraryfarns

    Sequence, based on observed residues (ATOM records): (download) 
    >6ygsA (A:)
drprfsfsiaaregkartgtiemkrgvirtpafmpvgtaadiilgntyhlmlrpgaeria
klgglhsfmgwdrpiltdsggyqvmslssltkqseegvtfkhmlspersieiqhllgsdi
vmafdectpypatpsraassmersmrwakrsrdafdsrkeqaenaalfgiqqgsvfenlr
qqsadalaeigfdgyavgglavgegqdemfrvldfsvpmlpddkphylmgvgkpddivga
vergidmfdvlptrsgrngqaftwdgpinirnarfsedlkpldsechcavcqkwsrayih
hlirageilgamlmtehniafyqqlmqkirdsisegrfsqfaqdfraryfa