PDB entry 6ygj

View 6ygj on RCSB PDB site
Description: small-molecule stabilizer of 14-3-3 and the carbohydrate response element binding protein (chrebp) protein-protein interaction
Deposited on 2020-03-27, released 2020-09-16
The last revision was dated 2020-09-16, with a file datestamp of 2020-09-11.
Experiment type: XRAY
Resolution: 2.07 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 14-3-3 protein beta/alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: Ywhab
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Carbohydrate-responsive element-binding protein
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NP71 (0-End)
      • conflict (19)
  • Chain 'F':
    Compound: 14-3-3 protein beta/alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: Ywhab
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Carbohydrate-responsive element-binding protein
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NP71 (0-End)
      • conflict (19)
  • Heterogens: OQE, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ygjA (A:)
dkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrsswrv
issieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfylkm
kgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfyyei
lnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwts

    Sequence, based on observed residues (ATOM records):
    >6ygjA (A:)
dkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrsswrv
issieqktnekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfylkmkg
dyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfyyeiln
spekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwts

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ygjB (B:)
rdkirlnnaiwrawyiqyvqr

    Sequence, based on observed residues (ATOM records):
    >6ygjB (B:)
rdkirlnnaiwrawyiqyvq

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ygjF (F:)
tmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrssw
rvissieqkternekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfyl
kmkgdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfyy
eilnspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwts

    Sequence, based on observed residues (ATOM records):
    >6ygjF (F:)
tmdkselvqkaklaeqaeryddmaaamkavteqghelsneernllsvayknvvgarrssw
rvissieqknekkqqmgkeyrekieaelqdicndvlelldkylipnatqpeskvfylkmk
gdyfrylsevasgdnkqttvsnsqqayqeafeiskkemqpthpirlglalnfsvfyyeil
nspekacslaktafdeaiaeldtlneesykdstlimqllrdnltlwts

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6ygjI (I:)
rdkirlnnaiwrawyiqyvqr

    Sequence, based on observed residues (ATOM records):
    >6ygjI (I:)
rdkirlnnaiwrawyiqyvq