PDB entry 6yf2

View 6yf2 on RCSB PDB site
Description: FKBP12 in complex with the BMP potentiator compound 6 at 1.03A resolution
Class: isomerase
Keywords: immunosuppression, immunosuppressant, bmp enhancer program, isomerase
Deposited on 2020-03-25, released 2021-03-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 1.03 Å
R-factor: N/A
AEROSPACI score: 0.88 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptidyl-prolyl cis-trans isomerase FKBP1A
    Species: Homo sapiens [TaxId:9606]
    Gene: FKBP1A, FKBP1, FKBP12
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62942 (2-108)
      • expression tag (1)
    Domains in SCOPe 2.08: d6yf2a1, d6yf2a2
  • Heterogens: OP5, CD, CL, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yf2A (A:)
gpgvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirg
weegvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle

    Sequence, based on observed residues (ATOM records): (download) 
    >6yf2A (A:)
pgvqvetispgdgrtfpkrgqtcvvhytgmledgkkfdssrdrnkpfkfmlgkqevirgw
eegvaqmsvgqrakltispdyaygatghpgiipphatlvfdvellkle