PDB entry 6yev

View 6yev on RCSB PDB site
Description: Crystal structure of MsrA C206 and Trx C35S complex from Escherichia coli
Class: oxidoreductase
Keywords: Reductase, S-Methionine sulfoxide reductase, Oxidative stress, OXIDOREDUCTASE, complex, thioredoxin
Deposited on 2020-03-25, released 2021-04-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 2.94 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptide methionine sulfoxide reductase msrA
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: msrA, pms, b4219, JW4178
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A744 (Start-211)
      • engineered mutation (51)
      • engineered mutation (86)
      • engineered mutation (198)
    Domains in SCOPe 2.08: d6yeva_
  • Chain 'B':
    Compound: Peptide methionine sulfoxide reductase msrA
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: msrA, pms, b4219, JW4178
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A744
      • engineered mutation (51)
      • engineered mutation (86)
      • engineered mutation (198)
    Domains in SCOPe 2.08: d6yevb_
  • Chain 'C':
    Compound: Peptide methionine sulfoxide reductase msrA
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: msrA, pms, b4219, JW4178
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A744
      • engineered mutation (51)
      • engineered mutation (86)
      • engineered mutation (198)
    Domains in SCOPe 2.08: d6yevc_
  • Chain 'D':
    Compound: Peptide methionine sulfoxide reductase msrA
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: msrA, pms, b4219, JW4178
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A744
      • engineered mutation (51)
      • engineered mutation (86)
      • engineered mutation (198)
    Domains in SCOPe 2.08: d6yevd_
  • Chain 'E':
    Compound: Thioredoxin 1
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: trxA, fipA, tsnC, b3781, JW5856
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AA25
      • engineered mutation (35)
    Domains in SCOPe 2.08: d6yeve_
  • Chain 'F':
    Compound: Thioredoxin 1
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: trxA, fipA, tsnC, b3781, JW5856
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AA25 (Start-108)
      • engineered mutation (35)
    Domains in SCOPe 2.08: d6yevf_
  • Chain 'G':
    Compound: Thioredoxin 1
    Species: Escherichia coli K-12 [TaxId:83333]
    Gene: trxA, fipA, tsnC, b3781, JW5856
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0AA25 (Start-108)
      • engineered mutation (35)
    Domains in SCOPe 2.08: d6yevg_
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6yevA (A:)
mslfdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlf
wqlpgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhd
paqgmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpf
yyaeddhqqylhknpygyagiggigvclppea

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevA (A:)
fdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlfwql
pgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhdpaq
gmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpfyya
eddhqqylhknpygyagiggigvclppea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6yevB (B:)
mslfdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlf
wqlpgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhd
paqgmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpf
yyaeddhqqylhknpygyagiggigvclppea

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevB (B:)
dkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlfwqlp
gvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhdpaqg
mrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpfyyae
ddhqqylhknpygyagiggigvclppe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6yevC (C:)
mslfdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlf
wqlpgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhd
paqgmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpf
yyaeddhqqylhknpygyagiggigvclppea

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevC (C:)
fdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlfwql
pgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhdpaq
gmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpfyya
eddhqqylhknpygyagiggigvclppe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6yevD (D:)
mslfdkkhlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlf
wqlpgvystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhd
paqgmrqgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpf
yyaeddhqqylhknpygyagiggigvclppea

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevD (D:)
khlvspadalpgrntpmpvatlhavnghsmtnvpdgmeiaifamgafwgverlfwqlpgv
ystaagytggytpnptyrevasgdtghaeavrivydpsvisyeqllqvfwenhdpaqgmr
qgndhgtqyrsaiypltpeqdaaaraslerfqaamlaadddrhitteianatpfyyaedd
hqqylhknpygyagiggigvc

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6yevE (E:)
msdkiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvakln
idqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevE (E:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefl

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6yevF (F:)
msdkiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvakln
idqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevF (F:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6yevG (G:)
msdkiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvakln
idqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >6yevG (G:)
kiihltddsfdtdvlkadgailvdfwaewcgpskmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla