PDB entry 6ye3

View 6ye3 on RCSB PDB site
Description: IL-2 in complex with a Fab fragment from UFKA-20
Class: protein binding
Keywords: IL-2, Fab, Treg, PROTEIN BINDING
Deposited on 2020-03-23, released 2020-12-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-30, with a file datestamp of 2020-12-25.
Experiment type: XRAY
Resolution: 2.89 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chains: A,D,G
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-End)
  • Chain 'B':
    Compound: Chains: B,E,H
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-218)
    Domains in SCOPe 2.08: d6ye3b1, d6ye3b2
  • Chain 'C':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ye3c_
  • Chain 'D':
    Compound: Chains: A,D,G
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-End)
  • Chain 'E':
    Compound: Chains: B,E,H
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-218)
    Domains in SCOPe 2.08: d6ye3e1, d6ye3e2
  • Chain 'F':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ye3f_
  • Chain 'G':
    Compound: Chains: A,D,G
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-End)
  • Chain 'H':
    Compound: Chains: B,E,H
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6YE3 (0-218)
    Domains in SCOPe 2.08: d6ye3h1, d6ye3h2
  • Chain 'I':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ye3i_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ye3B (B:)
divmtqspsslavsvgqkvtmsckssqsllnsanqknylawyqqkpgqspklliyfastr
esgvpdrfigsgsgtdftlnissvqaedladyfcqqyysappwtfgggtkleikradaap
tvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdsty
smsstltltkdeyerhnsytceathktstspivksfnrn

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ye3C (C:)
maptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcl
eeelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativefln
rwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ye3C (C:)
tssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleee
lkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwi
tfcqsiistlt

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ye3E (E:)
divmtqspsslavsvgqkvtmsckssqsllnsanqknylawyqqkpgqspklliyfastr
esgvpdrfigsgsgtdftlnissvqaedladyfcqqyysappwtfgggtkleikradaap
tvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdsty
smsstltltkdeyerhnsytceathktstspivksfnrn

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6ye3F (F:)
maptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcl
eeelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativefln
rwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ye3F (F:)
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrwit
fcqsiistlt

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6ye3H (H:)
divmtqspsslavsvgqkvtmsckssqsllnsanqknylawyqqkpgqspklliyfastr
esgvpdrfigsgsgtdftlnissvqaedladyfcqqyysappwtfgggtkleikradaap
tvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdsty
smsstltltkdeyerhnsytceathktstspivksfnrn

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6ye3I (I:)
maptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcl
eeelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativefln
rwitfcqsiistlt

    Sequence, based on observed residues (ATOM records): (download) 
    >6ye3I (I:)
ptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqclee
elkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnrw
itfcqsiistl