PDB entry 6ybg

View 6ybg on RCSB PDB site
Description: Structure of Mcl-1 in complex with compound 2g
Class: apoptosis
Keywords: Apoptosis, Apoptosis-inhibitor complex, Mcl-1, S64315, small molecule inhibitor
Deposited on 2020-03-17, released 2020-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-12-02, with a file datestamp of 2020-11-27.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ybga_
  • Chain 'B':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ybgb_
  • Heterogens: OJT, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ybgA (A:)
mhhhhhhlvprgsedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvg
dgvqrnhetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakh
lktinqescieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6ybgA (A:)
delyrqsleiisrylreqatgakdsgatsrkaletlrrvgdgvqrnhetafqgmlrkldi
kneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitdv
lvrtkrdwlvkqrgwdgfveffh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ybgB (B:)
mhhhhhhlvprgsedelyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvg
dgvqrnhetafqgmlrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakh
lktinqescieplaesitdvlvrtkrdwlvkqrgwdgfveffhvedlegg

    Sequence, based on observed residues (ATOM records): (download) 
    >6ybgB (B:)
delyrqsleiisrylreqatgakdgatsrkaletlrrvgdgvqrnhetafqgmlrkldik
neddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaesitdvl
vrtkrdwlvkqrgwdgfveffhve