PDB entry 6y8o

View 6y8o on RCSB PDB site
Description: Mycobacterium smegmatis GyrB 22kDa ATPase sub-domain in complex with novobiocin
Class: DNA binding protein
Keywords: Binding Sites, DNA Gyrase, inhibitors, , novobiocin IV, ISOMERASE, DNA BINDING PROTEIN
Deposited on 2020-03-05, released 2020-08-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-30, with a file datestamp of 2020-09-25.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA gyrase subunit b
    Species: Mycolicibacterium smegmatis [TaxId:1772]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C559 (Start-233)
      • engineered mutation (223-224)
    Domains in SCOPe 2.08: d6y8oa_
  • Chain 'B':
    Compound: DNA gyrase subunit b
    Species: Mycolicibacterium smegmatis [TaxId:1772]
    Gene: GYRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0C559 (Start-233)
      • engineered mutation (223-224)
    Domains in SCOPe 2.08: d6y8ob_
  • Heterogens: NOV, EDO, ACT, NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6y8oA (A:)
mhhhhhhssgrenlyfqgmpkeygadsitilegleavrkrpgmyigstgerglhhliwev
vdnavdeamagfatrvdvkihadgsvevrddgrgipvemhatgmptidvvmtqlhaggkf
dgetyavsgglhgvgvsvvnalstrleatvlrdgyewfqyydrsvpgklkqggetketgt
tirfwadpeifettdynfetvarrlqemaflnkgltieltderdgkhrvfhypg

    Sequence, based on observed residues (ATOM records): (download) 
    >6y8oA (A:)
sitilegleavrkrpgmyigstgerglhhliwevvdnavdeamagfatrvdvkihadgsv
evrddgrgipvemhatgmptidvvmtqvgvsvvnalstrleatvlrdgyewfqyydrsvp
gklkqggetketgttirfwadpeifettdynfetvarrlqemaflnkgltieltderdgk
hrvfhypg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6y8oB (B:)
mhhhhhhssgrenlyfqgmpkeygadsitilegleavrkrpgmyigstgerglhhliwev
vdnavdeamagfatrvdvkihadgsvevrddgrgipvemhatgmptidvvmtqlhaggkf
dgetyavsgglhgvgvsvvnalstrleatvlrdgyewfqyydrsvpgklkqggetketgt
tirfwadpeifettdynfetvarrlqemaflnkgltieltderdgkhrvfhypg

    Sequence, based on observed residues (ATOM records): (download) 
    >6y8oB (B:)
tilegleavrkrpgmyigstgerglhhliwevvdnavdeamagfatrvdvkihadgsvev
rddgrgipvemhatgmptidvvmtqvgvsvvnalstrleatvlrdgyewfqyydrsvpgk
lkqggetketgttirfwadpeifettdynfetvarrlqemaflnkgltieltderdgkhr
vfhypg