PDB entry 6y5v

View 6y5v on RCSB PDB site
Description: structure of human potassium chloride transporter kcc3b (s45d/t940d/t997d) in kcl
Deposited on 2020-02-25, released 2020-07-15
The last revision was dated 2021-07-28, with a file datestamp of 2021-07-23.
Experiment type: EM
Resolution: 4.08 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Solute carrier family 12 member 6
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC12A6, KCC3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHW9 (0-1098)
      • conflict (44)
      • conflict (939)
      • conflict (996)
      • expression tag (1099)
  • Chain 'B':
    Compound: Solute carrier family 12 member 6
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC12A6, KCC3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UHW9 (0-1098)
      • conflict (44)
      • conflict (939)
      • conflict (996)
      • expression tag (1099)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6y5vA (A:)
mphftvtkvedpeegaaasisqepsladikariqdsdepdlsqnditgehsqllddghkk
arnaylnnsnyeegdeyfdknlalfeeemdtrpkvssllnrmanytnltqgakeheeaen
itegkkkptktpqmgtfmgvylpclqnifgvilflrltwvvgtagvlqafaivlicccct
mltaismsaiatngvvpaggsyfmisralgpefggavglcfylgttfaaamyilgaieif
lvyivpraaifhsddalkesaamlnnmrvygtaflvlmvlvvfigvryvnkfaslflacv
ivsilaiyagaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcn
ssqffnatcdeyfvhnnvtsiqgipglasgiitenlwsnylpkgeiiekpsakssdvlgs
lnheyvlvdittsftllvgiffpsvtgimagsnrsgdlkdaqksipigtilailttsfvy
lsnvvlfgaciegvvlrdkfgdavkgnlvvgtlswpspwvivigsffstcgaglqsltga
prllqaiakdniipflrvfghskangeptwallltaaiaelgiliasldlvapilsmffl
mcylfvnlacalqtllrtpnwrprfryyhwalsfmgmsiclalmfisswyyaivamviag
miykyieyqgaekewgdgirglslsaarfallrleegpphtknwrpqllvllkldedlhv
khprlltfasqlkagkgltivgsvivgnflenygealaaeqtikhlmeaekvkgfcqlvv
aaklregishliqscglggmkhntvvmgwpngwrqsedarawktfigtvrvttaahlall
vaknisffpsnveqfsegnidvwwivhdggmlmllpfllkqhkvwrkcsiriftvaqled
nsiqmkkdlatflyhlrieaevevvemhdsdisaytyerdlmmeqrsqmlrhmrlskter
dreaqlvkdrnsmlrltsigsdedeetetyqekvhmdwtkdkymasrgqkaksmegfqdl
lnmrpdqsnvrrmhtavklnevivnksheaklvllnmpgpprnpegdenymeflevlteg
lervllvrgggsevitiysa

    Sequence, based on observed residues (ATOM records):
    >6y5vA (A:)
manytnltqgakeheeaeniqmgtfmgvylpclqnifgvilflrltwvvgtagvlqafai
vlicccctmltaismsaiatngvvpaggsyfmisralgpefggavglcfylgttfaaamy
ilgaieiflvyivpsaamlnnmrvygtaflvlmvlvvfigvryvnkfaslflacvivsil
aiyagaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqff
natcdeyfvhnnvtsiqgipglasgiitenlwsnylpkgeiiekpsakssdvlgslnhey
vlvdittsftllvgiffpsvtgimagsnrsgdlkdaqksipigtilailttsfvylsnvv
lfgaciegvvlrdkfgdavkgnlvvgtlswpspwvivigsffstcgaglqsltgaprllq
aiakdniipflrvfghskangeptwallltaaiaelgiliasldlvapilsmfflmcylf
vnlacalqtllrtpnwrprfryyhwalsfmgmsiclalmfisswyyaivamviagmiyky
ieyqgaekewgdgirglslsaarfallrleegpphtknwrpqllvllkldedlhvkhprl
ltfasqlkagkgltivgsvivgnflenygealaaeqtikhlmeaekvkgfcqlvvaaklr
egishliqscglggmkhntvvmgwpngwrqsedarawktfigtvrvttaahlallvakni
sffpsnveqfsegnidvwwivhdggmlmllpfllkqhkvwrkcsiriftvamkkdlatfl
yhlrieaevevvemhdsdisaytyerdlmmeqrsnvrrmhtavklnevivnksheaklvl
lnmpgpprnpegdenymeflevlteglervllvrgggse

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6y5vB (B:)
mphftvtkvedpeegaaasisqepsladikariqdsdepdlsqnditgehsqllddghkk
arnaylnnsnyeegdeyfdknlalfeeemdtrpkvssllnrmanytnltqgakeheeaen
itegkkkptktpqmgtfmgvylpclqnifgvilflrltwvvgtagvlqafaivlicccct
mltaismsaiatngvvpaggsyfmisralgpefggavglcfylgttfaaamyilgaieif
lvyivpraaifhsddalkesaamlnnmrvygtaflvlmvlvvfigvryvnkfaslflacv
ivsilaiyagaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcn
ssqffnatcdeyfvhnnvtsiqgipglasgiitenlwsnylpkgeiiekpsakssdvlgs
lnheyvlvdittsftllvgiffpsvtgimagsnrsgdlkdaqksipigtilailttsfvy
lsnvvlfgaciegvvlrdkfgdavkgnlvvgtlswpspwvivigsffstcgaglqsltga
prllqaiakdniipflrvfghskangeptwallltaaiaelgiliasldlvapilsmffl
mcylfvnlacalqtllrtpnwrprfryyhwalsfmgmsiclalmfisswyyaivamviag
miykyieyqgaekewgdgirglslsaarfallrleegpphtknwrpqllvllkldedlhv
khprlltfasqlkagkgltivgsvivgnflenygealaaeqtikhlmeaekvkgfcqlvv
aaklregishliqscglggmkhntvvmgwpngwrqsedarawktfigtvrvttaahlall
vaknisffpsnveqfsegnidvwwivhdggmlmllpfllkqhkvwrkcsiriftvaqled
nsiqmkkdlatflyhlrieaevevvemhdsdisaytyerdlmmeqrsqmlrhmrlskter
dreaqlvkdrnsmlrltsigsdedeetetyqekvhmdwtkdkymasrgqkaksmegfqdl
lnmrpdqsnvrrmhtavklnevivnksheaklvllnmpgpprnpegdenymeflevlteg
lervllvrgggsevitiysa

    Sequence, based on observed residues (ATOM records):
    >6y5vB (B:)
manytnltqgakeheeaeniqmgtfmgvylpclqnifgvilflrltwvvgtagvlqafai
vlicccctmltaismsaiatngvvpaggsyfmisralgpefggavglcfylgttfaaamy
ilgaieiflvyivpsaamlnnmrvygtaflvlmvlvvfigvryvnkfaslflacvivsil
aiyagaikssfapphfpvcmlgnrtlssrhidvcsktkeinnmtvpsklwgffcnssqff
natcdeyfvhnnvtsiqgipglasgiitenlwsnylpkgeiiekpsakssdvlgslnhey
vlvdittsftllvgiffpsvtgimagsnrsgdlkdaqksipigtilailttsfvylsnvv
lfgaciegvvlrdkfgdavkgnlvvgtlswpspwvivigsffstcgaglqsltgaprllq
aiakdniipflrvfghskangeptwallltaaiaelgiliasldlvapilsmfflmcylf
vnlacalqtllrtpnwrprfryyhwalsfmgmsiclalmfisswyyaivamviagmiyky
ieyqgaekewgdgirglslsaarfallrleegpphtknwrpqllvllkldedlhvkhprl
ltfasqlkagkgltivgsvivgnflenygealaaeqtikhlmeaekvkgfcqlvvaaklr
egishliqscglggmkhntvvmgwpngwrqsedarawktfigtvrvttaahlallvakni
sffpsnveqfsegnidvwwivhdggmlmllpfllkqhkvwrkcsiriftvamkkdlatfl
yhlrieaevevvemhdsdisaytyerdlmmeqrsnvrrmhtavklnevivnksheaklvl
lnmpgpprnpegdenymeflevlteglervllvrgggse