PDB entry 6y59

View 6y59 on RCSB PDB site
Description: 5-ht3a receptor in salipro (apo, c5 symmetric)
Deposited on 2020-02-25, released 2020-12-23
The last revision was dated 2021-03-03, with a file datestamp of 2021-02-26.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23979 (Start-537)
      • insertion (352)
      • conflict (536)
  • Chain 'B':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23979 (Start-537)
      • insertion (352)
      • conflict (536)
  • Chain 'C':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23979 (Start-537)
      • insertion (352)
      • conflict (536)
  • Chain 'D':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23979 (Start-537)
      • insertion (352)
      • conflict (536)
  • Chain 'E':
    Compound: 5-hydroxytryptamine receptor 3A
    Species: Mus musculus [TaxId:10090]
    Gene: Htr3a, 5ht3, Htr3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23979 (Start-537)
      • insertion (352)
      • conflict (536)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6y59A (A:)
mwshpqfekgggsgggsgggswshpqfekgggsgggsgggswshpqfekgggsgggsggg
swshpqfekenlyfqgatqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvi
myailnvdeknqvlttyiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefv
dvgkspnipyvyvhhrgevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdin
itlwrspeevrsdksifinqgewellevfpqfkefsidisnsyaemkfyviirrrplfya
vslllpsiflmvvdivgfclppdsgervsfkitlllgysvfliivsdtlpataigtplig
vyfvvcmallvislaetifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrp
patfqanktddcsgsdllpamgnhcshvggpqdlektprgrgsplpppreaslavrgllq
elssirhflekrdemrevardwlrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >6y59A (A:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislaetifivrl
vhkqdvpdwlrhlvldriawilllqelssirhflekrdemrevardwlrvgyvldrllfr
iyllavlaysitlvtlwsiwhss

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6y59B (B:)
mwshpqfekgggsgggsgggswshpqfekgggsgggsgggswshpqfekgggsgggsggg
swshpqfekenlyfqgatqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvi
myailnvdeknqvlttyiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefv
dvgkspnipyvyvhhrgevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdin
itlwrspeevrsdksifinqgewellevfpqfkefsidisnsyaemkfyviirrrplfya
vslllpsiflmvvdivgfclppdsgervsfkitlllgysvfliivsdtlpataigtplig
vyfvvcmallvislaetifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrp
patfqanktddcsgsdllpamgnhcshvggpqdlektprgrgsplpppreaslavrgllq
elssirhflekrdemrevardwlrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >6y59B (B:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislaetifivrl
vhkqdvpdwlrhlvldriawilllqelssirhflekrdemrevardwlrvgyvldrllfr
iyllavlaysitlvtlwsiwhss

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6y59C (C:)
mwshpqfekgggsgggsgggswshpqfekgggsgggsgggswshpqfekgggsgggsggg
swshpqfekenlyfqgatqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvi
myailnvdeknqvlttyiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefv
dvgkspnipyvyvhhrgevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdin
itlwrspeevrsdksifinqgewellevfpqfkefsidisnsyaemkfyviirrrplfya
vslllpsiflmvvdivgfclppdsgervsfkitlllgysvfliivsdtlpataigtplig
vyfvvcmallvislaetifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrp
patfqanktddcsgsdllpamgnhcshvggpqdlektprgrgsplpppreaslavrgllq
elssirhflekrdemrevardwlrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >6y59C (C:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislaetifivrl
vhkqdvpdwlrhlvldriawilllqelssirhflekrdemrevardwlrvgyvldrllfr
iyllavlaysitlvtlwsiwhss

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6y59D (D:)
mwshpqfekgggsgggsgggswshpqfekgggsgggsgggswshpqfekgggsgggsggg
swshpqfekenlyfqgatqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvi
myailnvdeknqvlttyiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefv
dvgkspnipyvyvhhrgevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdin
itlwrspeevrsdksifinqgewellevfpqfkefsidisnsyaemkfyviirrrplfya
vslllpsiflmvvdivgfclppdsgervsfkitlllgysvfliivsdtlpataigtplig
vyfvvcmallvislaetifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrp
patfqanktddcsgsdllpamgnhcshvggpqdlektprgrgsplpppreaslavrgllq
elssirhflekrdemrevardwlrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >6y59D (D:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislaetifivrl
vhkqdvpdwlrhlvldriawilllqelssirhflekrdemrevardwlrvgyvldrllfr
iyllavlaysitlvtlwsiwhss

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6y59E (E:)
mwshpqfekgggsgggsgggswshpqfekgggsgggsgggswshpqfekgggsgggsggg
swshpqfekenlyfqgatqardttqpallrlsdhllanykkgvrpvrdwrkpttvsidvi
myailnvdeknqvlttyiwyrqywtdeflqwtpedfdnvtklsiptdsiwvpdilinefv
dvgkspnipyvyvhhrgevqnykplqlvtacsldiynfpfdvqncsltftswlhtiqdin
itlwrspeevrsdksifinqgewellevfpqfkefsidisnsyaemkfyviirrrplfya
vslllpsiflmvvdivgfclppdsgervsfkitlllgysvfliivsdtlpataigtplig
vyfvvcmallvislaetifivrlvhkqdlqrpvpdwlrhlvldriawilclgeqpmahrp
patfqanktddcsgsdllpamgnhcshvggpqdlektprgrgsplpppreaslavrgllq
elssirhflekrdemrevardwlrvgyvldrllfriyllavlaysitlvtlwsiwhss

    Sequence, based on observed residues (ATOM records):
    >6y59E (E:)
tqpallrlsdhllanykkgvrpvrdwrkpttvsidvimyailnvdeknqvlttyiwyrqy
wtdeflqwtpedfdnvtklsiptdsiwvpdilinefvdvgkspnipyvyvhhrgevqnyk
plqlvtacsldiynfpfdvqncsltftswlhtiqdinitlwrspeevrsdksifinqgew
ellevfpqfkefsidisnsyaemkfyviirrrplfyavslllpsiflmvvdivgfclppd
sgervsfkitlllgysvfliivsdtlpataigtpligvyfvvcmallvislaetifivrl
vhkqdvpdwlrhlvldriawilllqelssirhflekrdemrevardwlrvgyvldrllfr
iyllavlaysitlvtlwsiwhss