PDB entry 6y4x

View 6y4x on RCSB PDB site
Description: Crystal structure of p38 in complex with SR72
Class: transferase
Keywords: kinase, kinase inhibitor, MAPK14, MAPK, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2020-02-23, released 2020-03-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2020-03-04, with a file datestamp of 2020-02-28.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Mus musculus [TaxId:10090]
    Gene: Mapk14, Crk1, Csbp1, Csbp2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6y4xa_
  • Heterogens: O8Q, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6y4xA (A:)
gmsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpf
qsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkc
qkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddem
tgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlv
gtpgaellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkrita
aqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeeme
s

    Sequence, based on observed residues (ATOM records): (download) 
    >6y4xA (A:)
msqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfq
siihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcq
kltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglayvatrwyr
apeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkk
issesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfa
qyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes